Are Viagra and Cialis the Same?


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Although Viagra and Cialis belong to the same class of drugs (PDE5 inhibitors) and are typically used to treat the same condition (erectile dysfunction), they are not the same.

That's because the active ingredient in Viagra is sildenafil, while the active ingredient in Cialis is tadalafil.

Ahead, we'll discuss the similarities and differences between Viagra and Cialis further.

Ingredients

As mentioned above, Viagra contains sildenafil, while Cialis contains tadalafil.

Sildenafil was patented in 1996 and released in 1998 by Pfizer (click here to learn more about the history of Viagra).

It works by inhibiting an enzyme called phosphodiesterase-5 (PDE5) that destroys cyclic guanosine monophosphate (cGMP), a compound which regulates blood flow. When PDE5 is inhibited, erectile function improves.

Meanwhile, Tadalafil was patented in 1994 and released in 2003 by Eli Lilly and Co.

Just like sildenafil, tadalafil works by inhibiting the PDE5 enzyme. However, the two ingredients are completely different compounds.

Treatments

Both Viagra and Cialis are typically prescribed to treat erectile dysfunction, a condition in which men struggle to get and keep erections.

Sildenafil, the active ingredient in Viagra, is also sold under the brand Revatio. Revatio is used to treat pulmonary arterial hypertension (PAH) and improve exercise capacity in men and women.

Similarly, tadalafil, the active ingredient in Cialis, is also sold under the brand Adcirca. Adcirca is also used to treat PAH and improve exercise capacity in both men and women.

Manufacturers

Viagra and Cialis are manufactured by two different companies, Pfizer and Eli Lilly and Co., respectively.

Pfizer was founded in 1948 in New York City. In 1906, the company's sales exceeded $3 million. In 2018, they surpassed $53 billion.

Today, Pfizer is one of the biggest pharmaceutical companies in the world (it stood in fifth place as of 2019). It employed more than 90,000 people globally as of May 15, 2019. Click here to learn more about Pfizer.

Eli Lilly and Co. was founded in 1876 in Indianapolis, Indiana. The business started with an investment of less than $2,000, but in 2018 alone earned more than $24 billion in revenue.

Eli Lilly and Co. is also one of the biggest pharmaceutical companies in the world (it claimed 10th place as of 2019). It employed over 38,000 people globally as of May 15, 2019.

Average Cost in the U.S.

In the U.S., Viagra typically retails for about $58.72 per pill, or $1,761.60 for 30 pills.

Cialis typically costs a bit more at about $72.87 per 10mg pill, or $2,186.24 for 30 pills.

If you think that seems expensive, you're exactly right: Outside the U.S., Viagra, Cialis and a slew of other prescription drugs are available for a fraction of the cost.

However, you can still save money on Viagra or Cialis by shopping from a reputable online pharmacy or pharmacy referral service.

For instance, depending on the dosage, brand-name Viagra from My Drug Center can cost as little as $8.27 per pill, while brand-name Cialis can cost just $4.15 per pill.

Longevity

For consumers, the biggest and most noticeable difference between Viagra and Cialis is their longevity.

Viagra usually starts to work within 30 to 60 minutes, and lasts for about four to eight hours. So, it's recommended that men take Viagra no more than four hours before sex.

On the other hand, Cialis usually starts to work within one to two hours, and lasts for up to 36 hours. So, men can take Cialis many hours (or even one to two days) before sex.

Which One Should You Choose?

Both Viagra and Cialis can treat erectile dysfunction, and both work by inhibiting the PDE5 enzyme.

What's more, the two drugs have similar common side effects including:

      Headaches.

      Flushing.

      Upset stomach.

      Back and/or muscle pain.

They also have similar drug interactions. For example, nitrate medications can cause harmful side effects when combined with either Cialis or Viagra.

So, whether you choose Cialis or Viagra depends largely on which best suits your lifestyle: Would it be more convenient for you to take a pill shortly before sex? Or, would you prefer to take a pill hours or even days beforehand?

As with any other medication, also consult with your doctor about any possible interactions with other drugs you may be taking.

Once you and your doctor have decided on the right choice for you, you can save money on either Viagra or Cialis by purchasing it from a trustworthy online pharmacy or pharmacy referral service.

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