Buy Zofran (Ondansetron) - Brand & Generic

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Zofran is an oral tablet made up of a 5HT3 receptor antagonist called ondansetron. We carry the brand choice and the generic alternative of this medication in 4mg and 8mg!

Zofran is prescribed to patients experiencing nausea and vomiting caused by surgery, cancer chemotherapy, or radiation treatment. Chemotherapy and radiation therapy are methods of killing cancer cells, however, they also kill healthy cells in the process. The affected (healthy) cells are usually located in the protective lining of the mouth and digestive tract which then causes irritation leading to symptoms of nausea and vomiting. These symptoms occur after surgery usually due to the anesthesia, but may also be caused by pain or discomfort.

Zofran (ondansetron) is effective at treating nausea and vomiting in post surgery, cancer chemotherapy, or radiation treatment because it is able to block the actions of the chemicals in the body that cause you to have these reactions (nausea and vomiting).

Your doctor will tell you before prescribing you Zofran (ondansetron) exactly how to take this medication. Follow his or her directions, they can usually be found on the prescription label if you forget.

Zofran is taken with or without food, usually at the start of your surgery, chemotherapy or radiation treatment. It should be swallowed whole with a glass of water.

Ensure the lid is tightly closed when not in use. Avoid keeping this medication in an area where it risks becoming wet or hot. Keep out of reach of children.

Do not use Zofran (ondansetron)

Zofran should not be used by those who are allergic to ondansetron or other similar medicines (dolasetron, granisetron, palonosetron), or if you also use apomorphine (Apokyn).

This medication is not approved for those under the age of 4 years old.

Dose adjustment or special precautions may be required

To ensure this medication is safe for you, tell your doctor if you have liver disease, an electrolyte imbalance, congestive heart failure, slow heartbeats, a personal or family history of long QT syndrome, or a blockage in your digestive tract (stomach or intestines).


This medication is not expected to harm an unborn baby however it is still recommended you tell your doctor if you are pregnant or plan on becoming pregnant.

It is not known if this medication will pass into breast milk or if it will harm a nursing infant. Tell your doctor if you are breast feeding.

Common side effects of Zofran (ondansetron) may include:

  • diarrhea or constipation;
  • headache;
  • drowsiness; or
  • tired feeling.

The above side effects should not alarm you.

Serious side effects of Zofran (ondansetron) may include:

  • severe constipation, stomach pain, or bloating;
  • headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
  • fast or pounding heartbeats;
  • jaundice (yellowing of the skin or eyes);
  • blurred vision or temporary vision loss (lasting from only a few minutes to several hours); or

high levels of serotonin in the body: agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.

If you have any of the above side effects or signs, contact your doctor right away.

Please note this is not a complete list of side effects. Not everyone experiences side effects; they are not guaranteed. If you do have side effects and they become unmanageable, consult your doctor about alternate medications.

What are medications that may interact with Zofran?

Medications that may interact with Zofran include narcotic medications or medications used to treat depression, nausea and vomiting, or a psychiatric disorder.

What should I avoid while being treated with Zofran?

You should avoid driving or other hazardous activities until you understand how this medication affects you; it could cause you to become impaired, affecting your thinking and reactions.

What are signs of an overdose and what should I do if I suspect one is occurring?

If you think an over dose is occurring, contact medical emergency services right away. Signs of an over dose may include sudden loss of vision, severe constipation, feeling light-headed, or fainting.

What should I do if I miss a dose?

Take the missed dose as soon as you remember or skip it if your next dose is approaching soon. Do not attempt to make up for a missed dose by doubling up on dosages.

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