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Zestril is an oral tablet consisting of an ACE (angiotensin converting enzyme) inhibitor called lisinopril. We carry the brand choice and generic alternative of Zestril in 5mg, 10mg, and 20mg!

Zestril is prescribed to help treat high blood pressure. A person who has narrow arteries and a heart that pumps more blood than normal will have high blood pressure. Blood pressure is the force of the blood against the walls of your blood vessels and when that force is high, it causes your heart to have to work harder which can cause damage. If high blood pressure goes untreated for too long, a person may risk developing heart problems (like heart attack or stroke) and kidney problems. Additionally, this medication may be used to treat congestive heart failure or to improve survival after a heart attack.

Zestril (lisinopril) is effective at treating high blood pressure (and other conditions) because lisinopril is able to relax blood vessels to allow easier blood flow, thus reducing blood pressure.

Follow only the directions given to you by your doctor. Do not take more or less of a dose than directed. For the full benefit of the medication, ensure you take it regularly and create a routine by taking it around the same time every day. Continue using this medication even if you feel well-high blood pressure often shows little to no symptoms; usually those with high blood pressure need to take medications for the rest of their lives.

While taking this medication, ensure you are drinking plenty of water and attending all doctor’s appointments for any necessary progress checks (such as blood pressure checks). This medication may be taken with or without food.


Do not use Zestril (lisinopril)

Do not use this medication if you are pregnant, have a history of angioedema, are allergic to lisinopril or any other ACE inhibitor, or if you have recently taken a medication containing sacubitril.

For those with diabetes or kidney disease; you cannot take this medication (Zestril) together with medications that contain aliskiren.

Dose adjustment or special precautions may be required

To ensure this medication is safe for you, tell your doctor if you have kidney disease, liver disease, or high levels of potassium in your blood.


If you become pregnant during treatment, discontinue use and tell your doctor right away. Injury or death can occur to the unborn baby if the mother takes this medication in the second or third trimester of pregnancy.

You should not breastfeed while using Zestril.

Side Effects

Common side effects of Zestril (lisinopril) may include:

headache, dizziness; cough; or chest pain.

The above side effects should not alarm you.

Serious side effects of Zestril (lisinopril) may include:

a light-headed feeling, like you might pass out; or fever, sore throat.

If you have any of the above side effects, contact your doctor right away.

Please note this is not a complete list of side effects. Not everyone experiences side effects; they are not guaranteed. If you do have side effects and they become unmanageable, consult your doctor about alternate medications.

Contact your doctor if you notice signs of…

high potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;

kidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or

liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).


What is Lisinopril?

Lisinopril is an oral medication available in tablet form. Lisinopril is another name for the medication Zestril; it is also the generic name for the medication. Both the brand and the generic are available for purchase in three different strengths; obtainable only with a valid prescription.


What type of drug is Lisinopril?

Lisinopril is an antihypertensive medication; it belongs to the drug class called angiotensin-converting-enzyme inhibitors, commonly referred to as ACE inhibitors.


What dosage does Lisinopril come in?

Lisinopril is available in a wide variety of strengths; at My Drug Center, lisinopril, as both the brand-name and generic product, is available in 5, 10, and 20 mg tablets.


What is Lisinopril used for?

Lisinopril is used for treatment of hypertension; a condition where blood pressure levels are much higher than normal which poses certain health complications if left untreated.


What does Lisinopril do?

Lisinopril lowers blood pressure; this helps lower the risk of cardiovascular complications such as heart attack and stroke. Other complications of hypertension include weakened and narrowed blood vessels in the kidneys (resulting in kidney damage or failure) and thickened, narrowed, or torn blood vessels in the eyes (resulting in vision loss), which can be prevented with proper hypertension treatment.


How does Lisinopril work?

Normally, blood vessels are wide, which is optimal for smooth blood flow; however in cases of hypertension, blood flow is limited. High blood pressure occurs when the blood vessels become swollen and inflamed, resulting in the blood vessels width becoming smaller, limiting the amount of blood able to flow through, and raising overall blood pressure levels. Lisinopril is effective at lowering blood pressure because of its capability to relax the blood vessels so they widen back to normal, allowing proper blood flow to be restored.


How long does it take for Lisinopril to work?

Lisinopril does not waste time; it begins lowering your blood pressure as soon as a few hours into treatment. Unfortunetly, it is unlikely you will feel the effects of lisinopril until you have completed a few weeks of proper treatment. 


What is the half life of Lisinopril?

The half-life of lisinopril is about 12.5 hours; the half life indicates how long it takes for approximately 50% of the drug to clear out of the system; every 12.5 hours, the amount of medication in the body will drop by 50%.


How long does Lisinopril stay in your system?

You can calculate how long it will take for the medication to clear out of your system using the medication’s half-life. It takes about 5 half-lives for a medication to clear out of the system. As previously mentioned, the half-life of lisinopril is roughly 12.5 hours, therefore it will take roughly 62.5 hours (12.6 hrs  x 5) to clear the system, which converts to roughly 2 and a half days.


What is the side effect of Lisinopril?

The one side effect that seems most common within lisinopril users is a cough. Not all possible side effects have been listed here; speak with a health care professional to learn more about the side effects of lisinopril.


How long does side effects of Lisinopril last?

Some side effects – like diarrhea or stomachache – may subside after the first few days of treatment. Other side effects – like persistent cough or headache – may also go away within a few days however they could take a few weeks of treatment before disappearing. Mild side effects usually go away within a few weeks and should not alarm you; severe side effects that do not go away after a few days or weeks may require your doctor’s attention.


What does Lisinopril look like?

Lisinopril, when sold as Zestril, will always come in tablet form. What may differ is the appearance of the tablet. When buying the brand-name medication, you may find the tablets round or oval and white, pink, or even yellow in color; this appearance may vary when buying a generic version or when purchasing any type of Zestril (brand or generic) internationally.


How much does Lisinopril cost without insurance?

Lisinopril, when sold as the brand medication Zestril, can be an expensive medication, especially without insurance. Zestril (84 tablets of 20mg) is sold in the United States for over a thousand dollars more than the cost of the brand as well as the generic version at My Drug Center; at our certified Canadian Pharmacy, 84 lisinopril (20mg) tablets cost only $34.00, obtainable with a valid prescription.


Who makes Zestril?

Zestril is made by a company founded in 1999 called AstraZeneca; it is a British-Swedish multinational pharmaceutical and biopharmaceutical company headquartered in the United Kingdom. The company’s main research and development centers can be found in Maryland (US), Sweden, and Poland.


When to take Lisinopril?

Some doctors may suggest taking your first dose at bedtime; the medication will be new to your body and may cause you to become dizzy. As you adjust to the medication, side effects may become less noticeable after each dose at which point, if no specific directions have been set in place, you may take the dose whenever is most convenient for you.

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