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Xiidra is a ophthalmic solution, administered into the eyes, consisting of a lymphocyte function-associated antigen-1 (LFA-1) antagonist called lifitegrast. We carry the brand choice of this medication in 5%. 

Xiidra is prescribed to help treat dry eye disease. This is a condition that occurs when your tear ducts are not providing adequate lubrication for your eyes, usually either because you don’t produce enough tears or produce poor-quality tears. Dry eyes feel uncomfortable, usually a stinging or burning sensation in your eyes; you may also have stringy mucus in or around your eyes, eye redness, or a sensation of having something in your eye. Dry eyes can be caused by decreased tear production, as mentioned previously, but it can also be caused by increased evaporation. Increased evaporation can include wind, smoke, or dry air, blinking less often (like when your reading or doing other activities that require concentration), or eyelid problems.

Xiidra (lifitegrast) is effective at treating dry eye disease because it is able to block a certain protein on the surface of cells in your body. This protein is typically the cause of not being able to produce healthy tears or not being able to produce any tears at all.

Only take this medication the way that your doctor has directed you too. Taking the incorrect dose can lead to unwanted side effects, ineffectiveness, or adverse interactions; avoid taking more or less of a dose than recommended. This medication should be protected from heat, moisture, and light to avoid nullifying the medication; keep the lid tightly closed when not in use. Wash your hands and remove any contact lens before applying the drops.

Commonly, this medication is given as one drop in each eye twice per day, usually every 12 hours.

How to administer Xiidra (lifitegrast)

  • Tilt your head back
  • Look upward
  • Form a pouch by pulling down on your lower eye lid
  • Hold dropper above eye; apply 1 drop into the pouch
  • Look down and gently close your eyes for 1 – 2 minutes


Do not use Xiidra (lifitegrast)

Do not use this medication if you are allergic to lifitegrast or those under the age of 17 years old.

Dose adjustment or special precautions may be required

To ensure this medication is safe for you, tell your doctor about all medical conditions, all medications, and all drug allergies you may currently have.


It is not known if this drug will harm an unborn baby. Tell your doctor if you plan on becoming pregnant or if you are currently pregnant.

It has not been established if this medication will pass into breast milk or if it will harm a nursing infant. Tell your doctor if you are breast feeding.

Side Effects

Common side effects of Xiidra (lifitegrast) may include:

blurred vision; eye irritation; unusual or unpleasant taste in the mouth.

The above side effects should not alarm you.

Serious side effects of Xiidra (lifitegrast) may include:

vision problems; or severe eye redness or irritation.

If you have any of the above side effects, contact your doctor right away.

Please note this is not a complete list of side effects. Not everyone experiences side effects; they are not guaranteed. If you do have side effects and they become unmanageable, consult your doctor about alternate medications.


What is Xiidra?

This medication is a form of eye drops, and it is used to treat symptoms that come with dry eye disease.  How does Xiidra work? Generally this medication blocks out a certain protein on the surface of the cells in your body. This protein can cause your eyes to not produce enough tears or to produce tears that are not the correct consistency to keep your eyes at a healthy level. Xiidra is a sold in the singular dose of 5%. If you have any questions regarding this medication or any inquiries in general, feel free to give us a call at our toll free number 1-877-385-8998.      


How much is Xiidra?

Unfortunately, this medication isn’t covered by Medicare. Therefore, it doesn’t fall under any of their Tiers. So it may be a bit more expensive. However, you can find a more affordable price on an online Canadian Pharmacy such as My Drug Center.   


What are the side effects of Xiidra?

Some of the more common side effects to this medication are as follows; A Decrease In Sharpness Of Vision Called Reduced Visual Acuity, Eye Irritation, Taste Impairment. Keep in mind that these are not all of the side effects listed for this medication, and if you are experiencing any of these be sure to inform your doctor if they persist or worsen.


How to use Xiidra?

To apply this medication, be sure to wash your hands first. When ready tilt your head back and pull down the lower eyelid to form a pouch. Then hold the dropper directly over your eye and place the prescribed amount of drops into the pouch. Gently close your eyes and look down. Place a finger at the corner of your eye near your nose and apply a bit of pressure for 1 to 2 minutes before opening your eye again. Try not to blink or rub your eye. Repeat the procedure for the other eye if needed. And be sure to wash your hands afterwards as well.


Who makes Xiidra?

Xiidra is manufactured by Shire US Inc. Shire was a Jersey-registered specialty biopharmaceutical company. However, as of January 8, 2019. It was bought out by Takeda Pharmaceuticals. Shire itself originated in the United Kingdom, but they still have a home base in America. Takeda Pharmaceuticals is a Japanese international company.


How long does it take for Xiidra to work?

Once you begin treatment it will likely take a few weeks before you notice any improvements. You may even begin to feel your symptoms lessen within about two week’s time.

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