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Wellbutrin XL is an oral tablet consisting of an antidepressant called bupropion. We carry this medication in both the brand choice and generic alternative in 150mg!

Wellbutrin XL is used to treat major depressive disorder and seasonal affective disorder. It is thought that depression is caused due to a chemical imbalance in the brain, though the exact cause of this is unknown. What doctors do know is that there are certain risk factors that may make one more likely to develop depression, such as family history, substance abuse, stressful life situations or grief, injury, childhood abuse (physical or emotional), or having medical conditions such as a chronic life time condition (like diabetes) or a past mental illness (like anxiety). Depression symptoms include constant feelings of being sad or down, reduced concentration, lack of motivation, detachment from reality, appetite changes, sexy drive changes, substance abuse, suicidal thoughts or actions, self-isolation, and not wanting to participate in activities you usually enjoy doing. Depression can become fatal if a person is suicidal and decides to take their own life.

Wellbutrin XL (bupropion) is effective at treating depression-related conditions due to its ability to restore the balance of dopamine and norepinephrine in the brain.

Always follow directions given to you by your doctor. Most prescription labels have the directions written on them for your convenience. Do not suddenly stop taking this medication; the only time you should immediately discontinue use is if you have a seizure while using this medication.

You may take this medication with or without food, but the tablet must be swallowed whole; do not chew, crush, or break this tablet.

Store this medication at room temperature in a low risk area of heat, light, and moisture.


Do not use Wellbutrin XL (bupropion)

If you are allergic to bupropion or if you have a seizure disorder, an eating disorder, or if you have suddenly stopped using alcohol, seizure medications, or a sedative; do not use Wellbutrin XL.

Do not use this medication if you have used an MAO inhibitor in the last 14 days; a dangerous drug interaction may occur.

Do not use this medication if you are under the age of 18 years old.

Dose adjustment or special precautions may be required

Tell your doctor about all medications and medical conditions you currently have or use. Tell your doctor about your medical past as well, especially if you have ever had a head injury, seizures, or brain or spinal cord tumor, narrow-angle glaucoma, heart disease, high blood pressure, a heart attack, diabetes, kidney or liver disease, depression, bipolar disorder, or other mental illness, or if you drink alcohol.


It is not known if this medication will harm an unborn baby therefore you should tell your doctor if you are pregnant before starting treatment to discuss the risks and benefits. Do not stop taking this medication if you find out your pregnant during treatment; tell your doctor right away.

It may not be safe to breastfeed while on this medication; speak to your doctor about the risks and benefits of using this drug while breastfeeding.

This medication may cause seizures.

Side Effects

Common side effects of Wellbutrin XL (bupropion) may include:

dry mouth, sore throat, stuffy nose; ringing in the ears; blurred vision; nausea, vomiting, stomach pain, loss of appetite, constipation; sleep problems (insomnia); tremors, sweating, feeling anxious or nervous; fast heartbeats; confusion, agitation, hostility; rash; weight loss; increased urination; headache, dizziness; or muscle or joint pain.

The above side effects should not alarm you.

Serious side effects of Wellbutrin XL (bupropion) may include:

a seizure (convulsions); confusion, unusual changes in mood or behavior; blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; or fast or irregular heartbeats.

If you have any of the above side effects, contact your doctor right away.

Please note this is not a complete list of side effects. Not everyone experiences side effects; they are not guaranteed. If you do have side effects and they become unmanageable, consult your doctor about alternate medications.

Contact your doctor if you notice signs of…

 a manic episode: racing thoughts, increased energy, reckless behavior, feeling extremely happy or irritable, talking more than usual, severe problems with sleep.



What is Wellbutrin XL

Wellbutrin XL is a prescription medication; it is an extended-release tablet containing either 150 or 300 mg of bupropion HCL; what is bupropion HCL? Bupropion hydrochloride (HCL) is the hydrochloride salt of bupropion and the active ingredient responsible for the therapeutic effects of Wellbutrin XL. Almost half of all drug molecules used inside medications exists as salts. Some drugs, when formed as a weak acid or base, are not always optimal for absorption or dissolution in the body, which is necessary for effectiveness. Drug manufacturers will chemically change a drug into their salt form to enhance the absorption and overall effectiveness of the medication. However, bupropion hydrochloride (HCL) is commonly referred as just bupropion to prevent confusion.


What doses does Wellbutrin XL come in?

Wellbutrin XL is available in two different strengths; 150mg and 300mg. What is the max dose of Wellbutrin XL? The maximum dose for Wellbutrin XL is 450 mg per day for depression and 300 mg per day for seasonal affective disorder; the max dose for depression is only used after several weeks of unsuccessful treatment using a lower dose. What is the lowest dose of Wellbutrin XL? The lowest dose for Wellbutrin XL is 150mg once per day; this dose is used as the initial dose for the first 4-7 days of treatment, depending on the condition you are treating.


What class of drug is Wellbutrin XL?

Wellbutrin XL is an antidepressant; multiple different types of drug classes can be considered antidepressants. Antidepressants can include MAOIs, NDRIs, SSRIs, SNRIs, SARIs, TCAs and TeCAs, and miscellaneous antidepressants. Each drug class will have a different mechanism of action for antidepressant effects. So, what class of drug is bupropion specifically? Bupropion is an NDRI antidepressant, which stands for norepinephrine-dopamine reuptake inhibitor.


What is bupropion HCL used for?

Bupropion HCL is prescribed for the treatment or prevention of certain mental health disorders. Specifically conditions such as major depressive disorder and seasonal affective disorder. Patients with these mental health disorders can use Wellbutrin to help improve both mood and well-being, which may ultimately help with sleep and appetite problems. Wellbutrin XL has also been associated with the improvement of depression-related anxiety.


How does Wellbutrin XL work?

Disorders affecting mental health are often associated with low levels of dopamine, serotonin, and norepinephrine (natural chemicals found in the brain vital for sleep and emotional well-being). Nerves in the body, which release these chemicals, will sometimes absorb them back in to “recycle” and reuse them; this stops further production of the chemicals, leading to consistent low levels of the chemicals, which results in the mental health symptoms. How bupropion works to fix this: Wellbutrin XL, or bupropion, is able to stop the re-absorption of the chemicals so they cannot be re-used; this causes the body to boost production of the chemicals which balances the shortage and improves ones mental health. The actions of this medication are complex and not fully understood by doctors.


What are the side effects of Wellbutrin XL?

Common side effects of bupropion (Wellbutrin XL) include dry mouth, sore throat, stuffy nose, ringing in the ears, nausea and/or vomiting, and tremors; however, this is not a complete list of possible side effects.


Where to buy Wellbutrin XL online?

You can buy Wellbutrin XL online at With a valid prescription, you can access low prices on the brand-name medication; we even carry the generic alternative for an even lower cost, sold as bupropion XL. At My Drug Center, you can find bupropion XL for as low as $0.81 per tablet.


What is the generic name for Wellbutrin XL?

The generic name for Wellbutrin XL is named after the active ingredient, and since Wellbutrin XL is an extended release medication, the generic will also be extended release; therefore, the generic name for Wellbutrin XL is bupropion XL.


How long does it take for Wellbutrin XL to work?

The exact amount of time it takes for Wellbutrin XL to become effective will vary between each individual. So, on average, how long does it take for bupropion to work? It’ll take roughly 1-2 weeks for an improvement of sleep, energy, and/or appetite and about 4-6 weeks for an improvement of depressed mood and lack of interest in activities.


What is the difference between Wellbutrin XL and Wellbutrin SR?

Though more similar than different, Wellbutrin XL and Wellbutrin SR do share some differences. The main difference is the release method. XL stands for extended-release and SR stands for sustained-release; XL and SR tablets are also very similar, but XL tablets release the medicine more slowly than SR tablets and therefore the medicine received from the XL tablet will remain in the body for a little longer oppose to medicine received from an SR tablet. Other differences can be found within price, strength, and appearance. You can access affordable Wellbutrin XL online with a valid prescription at My Drug Center; you can buy Wellbutrin SR online as well at My Drug Center.


How much is bupropion without insurance?

Wellbutrin XL, or bupropion (XL), is an expensive medication in the United States, especially without insurance. The average retail cost in the United States is nearly 30 times more expensive than the cost for the same strength and quantity at My Drug Center. So, how much is Wellbutrin XL at My Drug Center? You can find generic Wellbutrin XL for as low as $69.00 for a supply of 30 (300mg) tablets, purchasable with a valid prescription.


How long does Wellbutrin XL stay in your system?

The half life of bupropion ranges between 12 and 30 hours; based off a series of studies, it averages at about 21 hours. With an average half life of 21 hours, you can expect bupropion to take a little over 4 days (105 hours) to clear out of your system. The amount of time it takes to clear the system will be influenced by the amount of times you’ve used it previously; those who use regularly will find it takes longer to clear the system. Hydroxybupropion, the metabolite of bupropion (created during metallization of the medication), will stay in the system for roughly 75-125 hours.


Who makes Wellbutrin XL?

Wellbutrin XL is manufactured by GlaxoSmithKline (GSK), a British multinational pharmaceutical founded in 2000.


How to take Wellbutrin XL?

Initial dosing commonly starts at 150mg once per day; after either 4 or 7 days (depending on the condition you are treating) you may increase to 300mg once per day (if needed). The most common maintenance dosage is 300mg once per day. How to properly take Wellbutrin XL; ensure the tablet is swallowed whole as it should not be chewed or crushed. You may take the dose with or without food, as directed by your doctor. When to take Wellbutrin XL: it is commonly taken in the morning. Ensure you are allowing a 24 hour interval in between each dose; do this by taking the medication at the same time each day. For seasonal affective disorder; treatment should be started in autumn (before depression starts), continued through winter, and discontinued (gradually) in early spring. You should follow directions given to you by your doctor if they are different than what has been listed here.


Why is Wellbutrin XL so expensive?

Wellbutrin isn’t always an expensive medication; it depends where you get your supply from. In many countries around the world, Wellbutrin XL is sold at an affordable low cost. In the United States, the same medication is sold for much more; it is a more popular medication, which comes entirely out of the patients pocket as Wellbutrin XL is not typically covered by insurance plans. However, similar to how you would buy medication locally, all you need is a valid prescription to access international prices for Wellbutrin XL. My Drug Center offers both the brand and the generic in many quantities and in both available strengths.


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