Vivelle-Dot Side effects can include:
Skin redness/irritation at the application site, nausea, vomiting, upset stomach, constipation, bloating, breast swelling and tenderness, nipple discharge, headache, back pain, joint pain, weight changes, acne, skin color changes, increased facial hair, thinning scalp hair, cold symptoms (stuffy nose, sneezing, sinus pain, sore throat), changes in your menstrual periods, or break-through bleeding.
More serious Vivelle-Dot side effects can be:
Mental/mood changes (such as depression, memory loss), breast lumps, unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged or recurrent bleeding), increased or new vaginal irritation/itching/odor/discharge, severe stomach or abdominal pain, persistent nausea or vomiting, yellowing eyes or skin, dark urine, swelling hands/ankles/feet, or increased thirst or urination.
If any side effects of Estradiol become unmanageable speak with your doctor or pharmacist for help in managing the side effects. For any serious side effects speak with your doctor right away for further treatment options.