Stiolto Respimat (Tiotropium/Olodaterol)

Brand Choice

  • Stiolto Respimat (Tiotropium/Olodaterol) 2.5mcg/2.5mcg

    Known as Spiolto internationally

    Prescription  Prescription Required

Generic Choice
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What is Stiolto Respimat (Tiotropium/Olodaterol) prescribed for?

Chronic obstructive pulmonary disease (COPD) is a long term lung condition that makes it difficult for you to breathe. This medication is used to control and prevent symptoms such as, wheezing, shortness of breath, that are caused by the ongoing lung disease chronic obstructive pulmonary disease. Controlling these symptoms helps you to stay active.

This medication is a combination of two drugs: Tiotropium and Olodaterol. Both of these medications work by relaxing the muscles around the airways in the lungs so they can open up and make breathing much easier on your. Tiotropium belongs to a class of drugs known as anticholinergics. Olodaterol belongs to the class of drugs known as long-acting inhaled beta-agonists (LABAs). Both drugs are also known as bronchodilators.

This medication must be used regularly to be effective. It will not work right away and should be used for relief of any sudden shortness of breath. You should have a quick relief inhaler for these types of situations.

Follow the instructions given to you about priming your inhaler if you are using it for the first time, or if you have not used it for more than 3 days, or for more than 21 days. When priming, spray towards the ground, not near your face.

This medication is to be inhaled by mouth, and usually 2 puffs a day, or as directed by your doctor.  You should wait at least 1 minute between each inhalation.  If you are using other inhalers at the same time be sure to wait at least one minute between the use of each medication.

Do not increase your dose or use this medication more often, or stop using it without first consulting your doctor. Your condition will not improve any faster and you run the risk of side effects.

Before taking this medication, it is best to advise your doctor if you are allergic to tiotropium or olodaterol; or to ipratropium; or to any other medications or allergies in general. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

You should also let your doctor know of all of your medical history. Especially if you have ever dealt with any of these experiences in the past; heart problems (such as chest pain, irregular heartbeat, previous heart attack), high blood pressure, diabetes, kidney disease, personal or family history of glaucoma (angle-closure type), seizures, overactive thyroid, difficulty urinating (such as due to an enlarged prostate).

Olodaterol may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using olodaterol, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using this medication safely.

While minor, some of these side effects may occur. They are as follows; Nervousness, shaking (tremor), or trouble sleeping may occur. However if any of these persist or worsen, it’s best to speak with your doctor right away.

Tell your doctor right away if you have any serious side effects, including: muscle cramps/weakness, increased thirst/urination, difficult/painful urination.

Get medical help right away if you have any very serious side effects, including: chest pain, fast/irregular heartbeat, severe dizziness, fainting, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights at night, blurred vision). Rarely, this medication may cause sudden, severe wheezing/trouble breathing right after you use it. If this happens, use your quick-relief inhaler and get medical help right away.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

What happens if I suddenly stop taking this medication?

There may be a relapse in symptoms as well as side effects. You should speak your doctor before stop taking this medication.

 

 What is the best dosage to take?

The diagnosis with your doctor will be able to determine the best dosage for your treatment. Work with your doctor closely for dosage and dosing schedules.

 

 What happens if I miss a dose?

You should take the missed dose as soon you realize you have forgotten. If the forgotten dose is closer to your next scheduled dose, take the next schedule dose to avoid overlapping in dose.

 

 What is the best way to store this medication?

This medication is stored at room temperature, and should be kept away from children and pets. Do not throw away this medication in the wastebasket. If you are uncertain how to dispose of this medication speak with your pharmacist for help in safely disposing of this medication.

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