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What is Starlix (Nateglinide) prescribed for?

This medication is used alone or with other medications to control high blood sugar, along with a proper diet and exercise program. This medication is used in people with type 2 diabetes.  

Controlling high blood sugars helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. And proper control of diabetes may also lessen your risk of a heart attack or stroke. This medication works by stimulating the body to produce more insulin, which is a natural substance that allows the body to properly use sugar from your diet.

Read the Patient Information leaflet if one is available from your pharmacist before you start using nateglinide and each time you get a refill. If you have any questions, consult your doctor

This medication is taken by mouth from 1 to 30 minutes before each main meal. And is usually taken 3 times a day. Do not take this medication no earlier than 30 minutes before a meal. And do not take a dose if you are skipping a meal. If you are having soup or any other liquid meals, a higher dose of this medication may be necessary to control your blood sugar. Speak with your doctor for more details.

Remember this dosage is based on your medical condition, number of meals per day, and your overall response to the treatment.

Check your blood sugar on a regular basis. Keep track of all of the results to determine the correct dose for you in any future treatments. Keeping this in mind, your doctor may change your dose as needed.


Before taking this medication, it is best to advise your doctor if you are allergic to Nateglinide or to any other medications or allergies in general. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

You should also let your doctor know of all of your medical history. Especially if you have ever dealt with any of these experiences in the past; kidney disease, liver disease, gout..

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.

Limit alcohol while taking this medication because it can increase the risk of developing low blood sugar.

Side Effects

While minor, some of these side effects may occur. They are as follows; Weight gain may occur. However if any of these persist or worsen, it’s best to speak with your doctor right away.

Nateglinide can cause low blood sugar (hypoglycemia) especially if you are taking other medicines for diabetes. Consuming large quantities of alcohol, not getting enough calories from food, or doing unusually heavy exercise may also lead to low blood sugar. Symptoms may include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, raise your blood sugar quickly by eating a quick source of sugar such as table sugar, honey, candy, or drinking a glass of fruit juice or non-diet soda. Check with your doctor or pharmacist to find out what you should do if you miss a meal.

Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. Your doctor may need to adjust your diabetes medication(s).

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.


What happens if I suddenly stop taking this medication?

There may be a relapse in symptoms as well as side effects. You should speak your doctor before stop taking this medication.


 What is the best dosage to take?

The diagnosis with your doctor will be able to determine the best dosage for your treatment. Work with your doctor closely for dosage and dosing schedules.


 What happens if I miss a dose?

You should take the missed dose as soon you realize you have forgotten. If the forgotten dose is closer to your next scheduled dose, take the next schedule dose to avoid overlapping in dose.


 What is the best way to store this medication?

This medication is stored at room temperature, and should be kept away from children and pets. Do not throw away this medication in the wastebasket. If you are uncertain how to dispose of this medication speak with your pharmacist for help in safely disposing of this medication.

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