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Propyl-Thyracil is an oral pill consisting of an antithyroid drug called propylthiouracil. We carry the brand choice of this medication in 50mg and 100mg!

Propyl-Thyracil is a treatment for hyperthyroidism, the medical name for an overactive thyroid. Overactive thyroids should be treated with other medications first and if not successful, that’s when Propyl-Thyracil will be prescribed. Hyperthyroidism occurs when the thyroid hormone level is high and is usually caused by an autoimmune disease, certain medications, a viral infection, thyroid cancer or inflammation, or high iodine levels. Thyroid hormones are naturally produced to help control body temperature, heart rate, growth, and weight, but when there are too many thyroid hormones, a person may experience weight loss, increased appetite, diarrhea, constipation, increased sweating and heat intolerance, nervousness, and many other unpleasant symptoms. If left untreated, an overactive thyroid can result in serious problems with the heart, bones, muscles, menstrual cycle, and fertility.

Propyl-Thyracil (propylthiouracil) is effective at treating hyperthyroidism because as a antithyroid drug, it is able to stop the thyroid gland from producing too much thyroid hormone, the cause of this condition and its symptoms.

Your doctor will tell you before prescribing you Propyl-Thyracil (propylthiouracil) exactly how to take this medication. Follow his or her directions, they can usually be found on the prescription label if you forget. Your dose will be based on your medical condition and response to treatment.

Take this medication by mouth with or without food. Take one tablet every 8 hours for a total of 3 doses per day. Use this medication regularly to get the most benefit out of it. If you condition does not improve, tell your doctor.


Do not use Propyl-Thyracil (propylthiouracil)

This drug should not be used by pregnant women. This medication can harm the baby or cause serious liver problems or death in the baby or the mother.

Do not use this drug if you are allergic to propylthiouracil.

Do not give this medicine to a child without the recommendation of a doctor.

Dose adjustment or special precautions may be required

Before using this medication, tell your doctor if you have ever had liver problems.


This drug can result in liver problems that can be life-threatening or may require a liver transplant. If you notice signs of liver damage (see side effects), discontinue use immediately and contact your doctor right away.

It may not be safe to breast feed while using this medication. If you are breastfeeding, consult your doctor.

Side Effects

Common side effects of Propyl-Thyracil (propylthiouracil) may include:

Nausea, vomiting, stomach pain; itching or tingling; joint or muscle pain; swollen glands; headache, drowsiness, dizziness; swelling in your hands or feet; decreased sense of taste; or hair loss.

The above side effects should not alarm you.

Serious side effects of Propyl-Thyracil (propylthiouracil) may include:

Fever, chills, sore throat, mouth sores, feeling light-headed; unusual bleeding; purple or red discoloration of your skin; skin rash, skin pain or swelling; pink or dark urine, foamy urine, little or no urination; or shortness of breath, or if you cough up blood.

If you have any of the above side effects, contact your doctor right away.

Please note this is not a complete list of side effects. Not everyone experiences side effects; they are not guaranteed. If you do have side effects and they become unmanageable, consult your doctor about alternate medications.

Contact your doctor if you notice signs of…

new or worsening symptoms of lupus: joint pain, and a skin rash on your cheeks or arms that worsens in sunlight;

liver damage, nausea, vomiting, upper stomach pain, itching, fever, tiredness, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).


What should I avoid while using Propyl-Thyracil?

Avoid driving or doing other hazardous activities until you understand how this medication affects you. Your reactions may be impaired after taking this drug.

What are signs over overdose?

If you notice signs of overdose, contact emergency services right away. Signs of overdose may include may include fever, chills, itching, upset stomach, nausea, vomiting, swelling, headache, or joint pain.

What is the recommended dose for an adult with overactive thyroid?

The recommended dose for an adult with overactive thyroid is 100mg every 8 hours as an initial dose. The maintenance dose may be increased to 100-150mg divided into 3 separate doses, taken every 8 hours.

Does this medication treat anything else beside overactive thyroid?

Associated with overactive thyroid, this medication will also treat thyrotoxicosis crisis or “thyroid storm”. This occurs in people with hyperthyroidism when they are under major stress such as trauma, heart attack, or infection.

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