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Proglycem is an oral suspension (liquid) medication consisting of a thiazide drug called diazoxide. We carry the brand choice of this medication in 100mg. 

Proglycem is used to treat low blood sugar (hypoglycemia). Proglycem should not be used to treat hypoglycemia caused by poor diet; this medication is used to treat hypoglycemia in patients who have a tumor on the pancreas, cancer, leucine sensitivity, or other conditions that cause the release of excess insulin. Insulin is the natural substance created in the pancreas which is used to store sugar in the blood for energy, lowering the amount of sugar found in the blood.

Proglycem (diazoxide) is effective at increasing blood sugar levels in those with hypoglycemia because diazoxide is able to prevent the pancreas from producing insulin, which allows the blood sugar to return to normal.

Instructions can be found on your prescription label; ensure you follow these directions very carefully. Be aware that your dose may change throughout treatment to ensure you get the best results. Avoid using more or less of this medication than prescribed; use this medication for the entire prescribed time; using regularly.

Shake the medication well just before you measure your dose. Using a dosing syringe or a special dose-measuring spoon or cup, carefully measure out your dose, taking it immediately afterwards.

If you notice the liquid has changed colors; do not use it and discard the rest of it.


Do not use this medication if you have occasional low blood sugar due to diet choices, or if you are allergic to diazoxide, hydrochlorothiazide (HCTZ), HydroDiuril, Hyzaar, Lopressor HCT, Vaseretic, Zestoretic, and other heart or blood pressure medicines.

Dose adjustment or special precautions may be required

Before using this product, tell your doctor if you have congestive heart failure, high blood pressure, kidney disease, gout, or low levels of potassium in your blood.


It is not known if this medication will harm an unborn baby. Consult your doctor before using this medication if you are pregnant or plan on becoming pregnant.

It is not known whether this drug passes into breast milk or if it will harm a nursing infant. Consult your doctor before using this medication if you are breastfeeding.

Side Effects

Common side effects of Proglycem (diazoxide) may include:

pounding heartbeats or fluttering in your chest; swelling in your hands, ankles, or feet; fine hair growth on the face, arms, and back (especially in women or children); nausea, vomiting, stomach pain, loss of appetite; diarrhea, constipation; or decreased sense of taste.

The above side effects should not alarm you.

Serious side effects of Proglycem (diazoxide) may include:

blurred vision, tunnel vision, eye pain, or seeing halos around lights; breathing problems in an infant or newborn treated with Proglycem; shortness of breath (even with mild exertion), swelling, rapid weight gain; or a light-headed feeling, like you might pass out.

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

 high blood sugar: increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.


How often is this medication taken?

Proglycem is commonly taken every 8-12 hours at evenly spaced intervals.

How long till I start feeling relief? How long will the relief last for?

Typically, this drug begins to work within 1 hour and can last for up to 8 hours.

When should I contact my doctor about using an alternative medication?

You should contact your doctor about switching medications if this medication does not show improvement of symptoms within 3 weeks.

What are signs of overdose? What should I do if I suspect an overdose may occur?

Signs of overdose may include extreme thirst or very dry mouth, fruity breath odor, stomach pain, vomiting, increased urination, confusion, and high ketones in the urine. If you suspect an overdose may occur, contact emergency medical services right away.

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