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Known as Amatine internationally


Proamatine is an oral tablet made up of a miscellaneous cardiovascular drug called midodrine. We carry this medication in the brand choice and generic alternative in 5mg!

Proamatine is prescribed to certain hypotension patients. Hypotension is another word for low blood pressure; Proamatine is specifically for those with low blood pressure that causes severe dizziness or lightheadedness (orthostatic hypotension). This type of medication should only be used when other treatments were not successful and the affects of low blood pressure begin interfering with everyday life.

Proamatine (midodrine) is effective at treating symptoms of orthostatic hypotension because it has a narrowing affect on the blood vessels. When blood vessels become narrow, the blood cannot flow as easily, the heart has to pump harder, and blood pressure becomes elevated, thus reducing symptoms of low blood pressure.

Follow only the directions given to you by your doctor. Do not take more or less of a dose than directed. For the full benefit of the medication, ensure you take it regularly and create a routine by taking it around the same time every day.

Proamatine is usually taken 3 times a day, with or without food, as directed by your doctor. Each dose should have a minimum of 3-4 hours in between. You should avoid taking this medication at the end of day as it is best taken during hours of the day when you will be standing; ideally, you should take your last dose at least 4 hours before bedtime and before the final evening meal. If you plan on taking a nap, save the dose for a different time of day.

Use this medication regularly to get the most benefit from it. For the longest shelf life, store this medication at room temperature away from children and areas where it risks becoming hot or wet.


Do not use Proamatine (midodrine)

Proamatine is not meant for those allergic to midodrine or those who have severe heart disease, kidney disease or if you are unable to urinate, pheochromocytoma, overactive thyroid, or high blood pressure even when laying down.

Dose adjustment or special precautions may be required

Before using this drug, tell your doctor if you have diabetes, glaucoma, a history of vision problems, liver disease, or a history of kidney disease.


It is not yet known if this drug passes into breast milk or if it has potential to harm a nursing infant, or an unborn baby in a pregnant woman if the mother takes Proamatine during pregnancy. Consult your doctor if you are pregnant or breast feeding.

Side Effects

Common side effects of Proamatine (midodrine) may include:

chills, goose bumps; numbness, tingling, or itching (especially in your scalp); headache, dizziness, tired feeling; nausea; or increased urination, painful or difficult urination, or sudden urge to urinate.

The above side effects should not alarm you.

Contact your doctor if you notice signs of…

severely slowed heart rate: weak pulse, severe dizziness or light-headed feeling; or

dangerously high blood pressure: severe headache, pounding sensation in your ears ("hearing" your heartbeats), blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure.


What is the recommended dose for an adult with severe dizziness caused by low blood pressure?

An adult with severe dizziness caused by low blood pressure should take 10mg three times a day.

Can children use this medication?

The effectiveness and safety of this drug has not been established in pediatric patients. Consult your doctor to learn if your child can use this medication.

Does Proamatine have any drug interactions?

Yes. Drugs that interact with midodrine (Proamatine) include digoxin, digitalis, droxidopa, antidepressants, asthma medicine, heart or blood pressure medicine, migraine medicine, thyroid medicine, and drugs that treat prostate disorder.

This is not a complete list of drugs that interact with midodrine (Proamatine). Consult your doctor to learn more about which drugs interact with midodrine.

What should I avoid while using this medication?

During treatment, avoid taking your dose too close to bedtime. This medication is best taken during the day time, when you are standing. For best effect, ensure your final dose of the day is taken at least 4 hours before bedtime.

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