Do not use Prilosec (omeprazole)
Prilosec should not be used by anyone who is allergic to omeprazole or other similar medications (such as esomeprazole, lansoprazole, pantoprazole, rabeprazole, Nexium, Prevacid, Protonix, and others), or if you take HIV medications that contain rilpivirine (such as Complera, Edurant, Odefsey, or Juluca).
Do not give this medication to a child. This should only be done under the approval of a doctor.
Dose adjustment or special precautions may be required
Before using Prilosec, tell your doctor if you have trouble or pain while swallowing, bloody or black stools, vomit that looks like blood or coffee grounds, heartburn that has lasted longer than 3 months, frequent chest pain, heartburn with wheezing, unexplained weight loss, nausea or vomiting, stomach pain, liver disease, low levels of magnesium in the blood, or osteoporosis or low bone mineral density.
Risks
You may be more likely to break a bone in your hip, wrist, or spine while using Prilosec long term or more than once per day. Consult your doctor if this concerns you.
Avoid using this medication until you have discussed the risks and benefits of this drug if you are pregnant or breast feeding.