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Prestalia is an oral tablet made up of an ACE inhibitor called perindopril and a calcium channel blocker called amlodipine besylate. Prestalia is also known internationally as Viacoram and can be purchased in 3.5mg/2.5mg, 7mg/5mg, and 14mg/10mg!

Prestalia is a medication used to treat high blood pressure. A person who has narrow arteries and a heart that pumps more blood than normal will have high blood pressure. High blood pressure is a condition in which there are little symptoms – if any at all – which is why it is important to have your blood pressure checked often. If high blood pressure goes untreated for too long, a person may risk developing heart problems (like heart attack or stroke) and kidney problems.

Prestalia (perindopril arginine/amlodipine besylate) is effective at treating high blood pressure because of its active ingredients and their capability to relax and widen the arteries which allows the blood to flow more easily.

Take Prestalia exactly the way your doctor has prescribed it to you. You may need frequent blood tests as well as having your blood pressure checked during the time of treatment. If you begin feeling well; do not stop taking Prestalia. Ensure you use the full prescribed amount.

This medication may be taken with or without food, taken at the same time each day. Stay hydrated during the course of treatment by drinking plenty of fluids.  It is recommended you drink 8 glasses of water (8oz/glass) per day.

Store this medication at room temperature away from moisture and heat. Avoid keeping it in an area accessible by children and pets.


Do not use Prestalia (perindopril arginine/amlodipine besylate)

You should not use this medication if you are allergic to perindopril arginine or amlodipine besylate.

Prestalia should not be used by those who have had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction), recently taken a heart medicine called sacubitril, or if you are allergic to any other ACE inhibitor.

Avoid using Prestalia if you have diabetes and take any medications that contain aliskiren.

Do not use Prestalia if you have kidney disease, or if you are pregnant.

Dose adjustment or special precautions may be required

Before starting treatment, tell your doctor if you’ve ever had heart disease, or a heart attack, high levels of potassium in your blood, kidney disease, liver disease, or if you are on a low-salt diet.


This drug has potential to terminate pregnancies or cause injury to an unborn baby if taken by a pregnant woman in her second or third trimester. Speak with your doctor if this applies to you.

You should not breast feed during the time of treatment with Prestalia.

Side Effects

Common side effects of Prestalia (perindopril arginine/amlodipine besylate) may include:

cough; headache, dizziness; or swelling in your hands or feet.

The above side effects should not alarm you.

Serious side effects of Prestalia (perindopril arginine/amlodipine besylate) may include:

a light-headed feeling, like you might pass out; swelling in your hands or feet, rapid weight gain; little or no urinating; new or worsened chest pain; or jaundice (yellowing of the skin or eyes).

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

high potassium: nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.


What is the best dosage to take?

For an adult with hypertension (high blood pressure), your initial dose should be 3.5mg/2.5mg taken once a day. The maximum dose is 14mg/10mg per day. Make sure you are following only the recommendation of your doctor.

Is this medication safe to use while pregnant or breastfeeding?

No. This medication has potential to cause injury or death to an unborn baby. If you are pregnant or plan on becoming pregnant; do not take Prestalia.

What should I avoid if I am using this product?

While being treated with Prestalia, you should avoid drinking alcohol as well as driving or participating in other hazardous activity until you understand how this medication affects you. This drug may cause you to become impaired; drinking alcohol may increase risk of this side effect and others.

Does it have any medication interactions?

Yes. Some drugs that interact with Prestalia include diuretics or “water pills”, heart or blood pressure medications, nonsteroidal anti-inflammatory drugs such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and others.

This is not a complete list of drugs that interact with Prestalia (perindopril arginine/amlodipine besylate). Consult your doctor to learn more about which drugs interact with Prestalia.

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