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What is Premarin prescribed for?

This medication provides hormone replacement therapy. During menopause, a woman's ovaries stop producing estrogen and progesterone hormones. Menopause is the time in a woman's life when her period stops. Patients often buy Premarin is used to treat menopause symptoms such as hot flashes and vaginal changes and to prevent osteoporosis (bone loss).

The prescribed Premarin dosage can make up for the lower amount of estrogen. Patients also buy Premarin to replace estrogen when they have ovarian failure or other conditions that cause a lack of natural estrogen in the body.

How does Premarin work?

Premarin tablets contain a conjugated estrogen dosage that works by supplying estrogens that the body may not produce in adequate quantities on its own. After oral consumption, Premarin is released gradually over the course of several hours. These estrogens help maintain the healthy function of the endocrine system, offer relief from menopausal symptoms, and strengthen the bones, which aids in the protection against osteoporosis.

In a large study of over two thousand postmenopausal women, treatment with Premarin for hot flushes was found to be statistically more effective than placebo from weeks 4 to 12. [1] If you are affected by severe hot flushes due to menopause, ask your doctor about a Premarin prescription today.

Before taking your prescribed Premarin dosage, read all the instructions that was provided by your pharmacist. Take the conjugated estrogens dosage orally as instructed by your doctor. This medication can be taken with or without food. Make sure you take Premarin at the same time each day to create a routine for yourself and to ensure an even spread of medication in your system. Premarin should taken on a regular basis to have optimal results. Do not change or increase your dose.


Premarin could cause adverse effects if you are allergic to its ingredients. Always inform your doctor about all of your allergies before starting treatment.

Speak with your doctor about any known medical conditions relating to vaginal bleeding, certain cancers, blood clots, stroke, heart disease, and swelling disorders. Additionally, Premarin may not be right for you if you have one or more of the following conditions:

  • High blood pressure
  • Diabetes
  • High cholesterol
  • Obesity
  • Lupus
  • Underactive thyroid
  • Mineral imbalance
  • Hormone problems
  • Uterus problems
  • Gallbladder disease
  • Asthma
  • Seizures
  • Migraine headaches
  • Blood disorders
  • Mental/mood disorders.

Tell your doctor about current medications or supplements to avoid interactions with Premarin.

Smoking tobacco can increase the risk of stroke, blood clots, high blood pressure, and heart attack in women over 35 who take Premarin. You should also avoid grapefruit, grapefruit juice, and other grapefruit-related products because they may interact with Premarin and cause adverse effects. [2] Before taking your Premarin dosage, speak with your doctor if you are bedridden or have recently had surgery. Being sedentary for extended periods can increase the risk of blood clots.

The Premarin dosage you take may make you develop problems wearing your contact lenses. Speak with your eye doctor if vision problems occur during your treatment with Premarin.

Premarin side effects can cause dark patches on your skin (melasma), and direct sunlight and exasperate this effect. Limit sun exposure, tanning booths, and heat lamps. Wear protective clothing in the sun and wear sunscreen in unprotected areas to avoid discolorations in your skin. 

Side Effects

Common side effects of Premarin include vomiting, nausea, cramps, and bloating. Other common side effects may include:

  • Breast tenderness
  • Headache
  • Weight changes
  • Appetite changes
  • Darkening of skin
  • Increased hair growth
  • Loss of scalp hair
  • Vaginal discharge
  • Changes in menstrual periods
  • Decreased sex drive
  • Tiredness or dizziness

Premarin may also cause rare but severe side effects, including breast lumps, unusual bleeding, or abdominal pain. Some patients experience persistent nausea, vomiting, jaundice (yellowing of the eyes or skin), dark urine, or increased thirst. [3] Speak to your doctor right away if these serious side effects affect you.


What is Premarin?

Premarin is a medication used by women, to help with the variety of symptoms that come along with menopause. Hot Flashes are but one example.

What are the side effects of Premarin?

Some of the most common side effects are an upset stomach, nausea, bloating, breast tenderness, headaches, and weight changes. These are not all of the side effects, for more information, speak with your doctor.

How fast does Premarin work?

Every patient is a little bit different; therefore it may take a few weeks before you begin to feel a change. The improvements can be gradual.

Premarin side effects when stopping?

Some of these withdrawal symptoms are the same symptoms that one would experience during menopause. Speak with your doctor for further information.

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