Prescription Icon Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.


Pramox HC lotion is a topical medication consisting of a combination of a steroid and an anesthetic called hydrocortisone and pramoxine. We carry the brand choice of this medication!

Pramox HC lotion is used to treat itching and discomfort caused by a variety of skin conditions, such as allergic reactions, eczema, minor burns, insect bites, or other skin conditions. The steroid in this medicine is called hydrocortisone, and it helps by reducing the actions of chemicals in the body that cause inflammation, while the anesthetic, called pramoxine, helps by interfering with pain signals sent from the nerves to the brain; this will allow a “numbing” effect which stops the body from feeling the pain.

Read all the directions on the label before proceeding with using this product.

Before applying the lotion, ensure you wash your hands and dry them thoroughly. Shake the bottle well before use. Use only a small amount of lotion on the affected area and gently rub it into the skin. Do not cover the area after applying the lotion unless otherwise directed by a doctor. Avoid using this product on the skin that is damaged or broken.

Store at room temperature in a low-risk area of moisture and heat.


Do not use Pramox HC Lotion (hydrocortisone/pramoxine)

Do not use this product if you are allergic to hydrocortisone or pramoxine or any other anesthetics or “numbing” medicines.

Do not give this product to a child. Only under a doctor’s approval should this medication be given to a child.

Dose adjustment or special precautions may be required

To make sure this product is safe for you, tell your doctor if you have liver disease, diabetes, eye problems, a stomach or intestinal disorder, a rectal sore or infection, or if you use any drugs that weak the immune system, including steroids.


This medication will not treat a bacterial, fungal, or viral skin infection. If you have a skin infection, you must have it treated before using this medication.

Tell your doctor if you are pregnant or breastfeeding. The effects of this drug have not been established on babies who are breastfeeding or still in the mother's womb.

Side Effects

Common side effects of Pramox HC Lotion (hydrocortisone/pramoxine) may include:

Burning, dryness, irritation, itching, or redness of skin rash

The above side effects should not alarm you.

Serious side effects of Pramox HC Lotion (hydrocortisone/pramoxine) may include:

Blood-containing blisters on the skin, changes in skin color, excess hair growth, increased skin sensitivity, lack of healing of skin condition, numbness in fingers, pain when the medication is applied

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

allergic reaction: sneezing and an itchy, runny or blocked nose (allergic rhinitis), itchy, red, or watering eyes (conjunctivitis), wheezing, chest tightness, shortness of breath, cough, a raised itchy, red rash (hives) or swollen lips, tongue, eyes or face.


What should I avoid while using this medication?

Avoid applying this lotion to swollen skin areas or deep puncture wounds. You may also want to avoid putting this lotion on areas of skin that are raw or blistered, such as a severe burn or abrasion, or skin fold areas, such as the underarms)

Are there other forms of this medication available?

Yes. At MyDrugCenter, we also carry Pramox HC Cream! Generally, those with dry skin should go for creams, while those with oily skin should go for lotions.

What if I miss a dose?

It is unlikely you will miss a dose as this lotion is generally applied as needed. If you are on a schedule, skip the missed dose if your next dose is soon.

Is this product safe for children to use?

Safety and effectiveness have not yet been established in pediatric patients.

Call To Complete

Need Help?
Call Our CareTeam


Our CareTeam Member will guide you to complete your order