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Parnate is an oral tablet made up of a antidepressant/monoamine oxidase inhibitor drug called tranylcypromine. We carry the brand choice of this medication in 10mg!

Parnate is prescribed to adults who suffer from depression that other medications were not successful in treating. Depression is a constant state of hopelessness, self-doubt, and sadness. People with depression may suffer from a loss of interest in activities you usually enjoy, changes in appetite and sleep patterns (sleeping too much or not much at all), self-isolation from friends and family, inability to concentrate or get things done, loss of motivation, irritability, thoughts of suicide, and even physical symptoms like nausea, headache, and stomach aches (sometimes caused by anxiety, which is often associated with depression). There are many factors that can lead to depression but the exact reason is unknown; it is thought that depression is caused when chemicals in the brain become unbalanced.

Parnate (tranylcypromine) is effective at treating depression because its active ingredient is able to restore the chemicals in the brain back to normal so symptoms of depression are less likely to occur.

When your doctor prescribes this medication to you, he or she will have explained to you exactly how to take it. Ensure you are following directions very carefully to avoid ineffectiveness, adverse interactions, and unwanted side effects.

Parnate is taken in divided doses by mouth, or as directed by your doctor. You may take this medication with or without food. Your dose will be determined by your doctor and based on your medical condition and response to therapy. The usual dose is equal to or less than 60mg per day.

Ensure you take this medication regularly to get the most benefit from it. It may lessen your chance of forgetting to take your dose if you take the tablet at the same time every day and use a pillbox or set a reminder on a phone or calendar.


Do not use Parnate (tranylcypromine)

This product should not be used by those who are allergic to tranylcypromine or if you have pheochromocytoma (tumor of the adrenal gland).

Many drugs will interact with this mediation and should not be taken with this drug. You should not take this drug if you also take other antidepressants, another MAO inhibitor, drugs that affect serotonin levels in your body, and more. Consult your doctor and go over all medications you are currently taking before starting treatment with this drug.

This medication is not approved for individuals under the age of 18 years old.

Dose adjustment or special precautions may be required

To ensure this medication is safe and effective for you to use, tell your doctor if you have ever had heart disease, high or low blood pressure, circulation problems, a stroke, bipolar disorder, liver disease, a thyroid disorder, headaches, diabetes, or a seizure.


Younger patients taking this drug have reported feeling thoughts of suicide.  Your doctor may want to have regular checkups to ensure the treatment has no potentially harmful side effects such as this one.

This drug may harm an unborn baby if taken by a pregnant mother. Consult your doctor about pregnancy before taking this medication.

During the time of treatment, you should not breast feed.

Side Effects

Common side effects of Parnate (tranylcypromine) may include:

dizziness, drowsiness; constipation; dry mouth, blurred vision; trouble sleeping; headache; or feeling shaky or excited.

The above side effects should not alarm you.

Serious side effects of Parnate (tranylcypromine) may include:

dilated pupils, vision problems, sensitivity to light; sudden and severe headache, neck pain or stiffness; numbness or weakness, problems with vision or speech; fast or pounding heartbeats; fever, cold sweat, nausea, vomiting; a light-headed feeling, like you might pass out; or a seizure.

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

a manic episode: racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative;

high levels of serotonin in the body: agitation, hallucinations, sweating, shivering, muscle stiffness, twitching, loss of coordination, vomiting, diarrhea; or

liver problems: loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes).


How should I store this medication?

Parnate (tranylcypromine) should be stored at room temperature. Protect Parnate (tranylcypromine) from heat and moisture. For safety measures, keep out of reach of children and pets.

What are some of the drug names that interact with Parnate?

Some of the drugs that interact with this one include Adderall (amphetamine / dextroamphetamine), Cymbalta (duloxetine), Prozac (fluoxetine), Ritalin (methylphenidate), trazodone, and Zoloft (sertraline).

Can I consume alcohol while using this drug?

No. Your doctor will have told you before treatment to not consume alcohol during treatment. It is important you follow this rule as dangerous side effects may occur if alcohol and tranylcypromine are mixed.

What should I avoid while using this medication?

During treatment with Parnate, you should avoid foods that are high in tyramine.  Tyramine-rich foods include air dried, aged, or fermented meats (including sausage and salami), beer on tap (not bottle or can), pickled herring, aged cheeses (including blue, boursault, brie, camembert, cheddar, gruyere, mozzarella, parmesan, Romano, Roquefort, and Swis), moldy or improperly stored meat, fish, poultry, or liver, soy sauce, miso soup, bean curd, fava beans, or yeast extracts.

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