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Known as Aventyl internationally


Pamelor is an oral capsule made up of a tricyclic antidepressant called nortriptyline. We carry the generic alternative and a brand choice of this medication in 10mg and 25mg. 

Pamelor is used to treat symptoms of depression. Depression can be described as a constant state of hopelessness, self doubt, and sadness. Symptoms of depression that can be treated with Pamelor include improving general mood and feelings of well-being, relieve anxiety (constant feelings of fear) and tension (physical and emotional stress), and increase your energy level. It is thought that depression is caused by an imbalance of chemicals in the brain.

Pamelor (nortriptyline) is effective at treating depression because it is able to affect the chemicals in the brain, resulting in the chemicals balancing out and symptoms of depression to lessen.

Follow all the directions given to you by your doctor very carefully. You may need to change your dose from time to time; ensure you are not taking more or less of a dose than recommended.

You may need to stop treatment temporarily if you need surgery of any kind. Tell your surgeon all medications you are currently taking.

Do not stop using this medication suddenly. Doing so may cause unpleasant withdrawal symptoms. Consult your doctor how to safely stop taking this medication.

Take this medication by mouth, usually done 1-4 times a day. Ensure you are taking the medication regularly to get the most benefit from it.


Do not use Pamelor (nortriptyline)

This product should not be used by those who are allergic to nortriptyline or similar antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, protriptyline, trimipramine), if you have recently had a heart attack, or if you allergic to certain seizure medicines (carbamazepine, eslicarbazepine, oxcarbazepine, rufinamide).

You should not use this product if you have used an MAO inhibitor in the past 2 weeks (14 days). A drug interaction could occur and is likely to be dangerous.

Dose adjustment or special precautions may be required

In order for your doctor to determine if this product is safe for you, tell your doctor if you have heart disease, or a history of heart attack, stroke, or seizures, bipolar disorder, schizophrenia or other mental illness, liver disease, a thyroid disorder, diabetes, narrow-angle glaucoma, or problems with urination.


Some younger patients have reported suicidal thoughts when first taking an antidepressant. Your doctor may want to check up on you to monitor you for any warning signs. Your family or caregivers should also be monitoring you for any changes in behavior or mood.

It has not been established if this medication will harm an unborn baby. If you are pregnant, ensure you speak with your doctor about the risks and benefits of this drug during pregnancy.

It has not been established if this medication passes into breast milk or if it will harm a nursing infant. If you are breast feeding, ensure you speak with your doctor about the possible risks and benefits of breasting feeding during this drug treatment.

This drug can sometimes cause a condition that affects the heart rhythm called long QT syndrome. This condition can sometimes be fatal and can cause serious (rarely fatal) fast or irregular heartbeats, dizziness and fainting and may require medical attention.

Side Effects

Common side effects of Pamelor (nortriptyline) may include:

nausea, vomiting, loss of appetite; anxiety, sleep problems (insomnia); dry mouth, unusual taste; little or no urinating; constipation; vision changes; breast swelling (in men or women); or decreased sex drive, impotence, or difficulty having an orgasm.

The above side effects should not alarm you.

Serious side effects of Pamelor (nortriptyline) may include:

blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; restless muscle movements in your eyes, tongue, jaw, or neck; a light-headed feeling, like you might pass out; seizure (convulsions); new or worsening chest pain, pounding heartbeats or fluttering in your chest; sudden numbness or weakness, problems with vision, speech, or balance; fever, sore throat, easy bruising, unusual bleeding; jaundice (yellowing of the skin or eyes);or painful or difficult urination. 

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

high levels of serotonin in the body: agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.

New or worsening symptoms: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.


What is Pamelor?

This medication is used as a treatment for mental and mood disorders such as depression. When taken, it may help improve your mood and feelings of well being; it may also relieve anxiety and tension and perhaps increase your energy level. When taken, it goes to work by affecting the balance of a natural chemical in the brain called a neurotransmitter. This medication comes in two different strengths which are 10mg and 25mg. If you have any questions regarding this medication or any inquiries in general, feel free to give us a call at our toll free number 1-877-385-8998.  


What are the side effects of Pamelor?

Some of the most common side effects to this medication are listed as follows; Fast heart rate, blurred vision, urinary retention, dry mouth, constipation, weight gain or loss, dizziness upon standing, tingly feeling, weakness, lack of coordination, unpleasant taste, nausea, ringing in your ears, breast swelling (in men and women), decreased sex drive, impotence, or difficulties in having a orgasm. Keep in mind that these are not the only side effects for this medication and if you have experienced any of these, be sure to notify your doctor if they persist or worsen.


How long does it take for Nortriptyline to take effect?

Many reports from patients indicate that it takes about 2 weeks for this medication to begin to work. However, it can take up to 2 months before you may gain the full benefit of this medication.

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