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Orudis E is an oral capsule containing a nonsteroidal anti-inflammatory drug (NAID) called Ketoprofen. We carry the generic alternative of this medication in 50mg. 

Orudis E is used to treat a variety of conditions that cause pain. Types of pain this drug treats includes menstrual pain, ankylosing spondylitis pain, a rheumatic disease causing pain and stiffness in the backbone, pain caused by a type of joint disorder due to gout, and headache pain caused by disorder of cranial blood vessels

Orudis E (Ketoprofen) is effective in treating pain due to ketoprofen ability to block out the production of certain natural substances in the body from occurring. When this action is blocked, so is inflammation.

Use this medication exactly the way your doctor has prescribed it to you. Do not take more or less of a dose, or for longer periods than recommended.

You may take with medication with food or milk if medications usually upset your stomach. Avoid chewing, crushing, or breaking the capsule open; swallow it whole.

Store at room temperature in a low risk area of moisture, heat, and light.


Do not use this medication prior to or following heart bypass surgery (coronary artery bypass graft, or CABG).

Orudis E should not be used by those who are allergic to ketoprofen or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs).

This medication is not approved for use in those under the age of 18.

Dose adjustment or special precautions may be required

Before using this product, tell your doctor about all medical conditions you have, more importantly, ensure you tell your doctor if you have heart disease, high blood pressure, high cholesterol, diabetes, a history of heart attack, stroke, or blood clots, asthma, liver or kidney disease, fluid retention, or if you smoke.


This drug can increase the risk of a fatal heart attack or stroke. This risk is higher in those who use this drug long term or take high doses, or if you have heart disease.

Stomach or intestinal bleeding can occur during the time of treatment with Orudis E, and can sometimes be fatal. This outcome is often times unexpected and happens without warning, usually in older adults.

Using this medication in the final 3 months of pregnancy could harm the baby. Only take this medication while pregnant under the advice of a doctor.

It is not known if this drug passes into breast milk or if it will harm a nursing infant. Avoid breast feeding while using this drug until you have spoken with your doctor.

Side Effects

Common side effects of Orudis E (ketoprofen) may include:

indigestion, stomach pain, nausea; diarrhea, constipation, gas; sleep problems (insomnia); feeling nervous; or swelling in your hands or feet.

The above side effects should not alarm you.

Serious side effects of Orudis E (ketoprofen) may include:

shortness of breath (even with mild exertion); swelling or rapid weight gain; or the first sign of any skin rash, no matter how mild.

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath;

stomach bleeding: bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

liver problems: nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

kidney problems: little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath;

low red blood cells (anemia): pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or

severe skin reaction: fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

allergic reaction: sneezing and an itchy, runny or blocked nose (allergic rhinitis), itchy, red, or watering eyes (conjunctivitis), wheezing, chest tightness, shortness of breath, cough, a raised itchy, red rash (hives) or swollen lips, tongue, eyes or face.


What is the average dose for an adult with osteoarthritis?

The average dose for an adult with osteoarthritis is 50mg taken four times a day, by mouth. Alternatively, you may take 75mg three times a day.

Is this product safe for children?

No. This medication has not been approved for use in those who are under the age of 18 years old.

What if I miss a dose?

Usually, this drug is taken as needed, so you likely won’t “miss a dose”. However, if you are a patient using this drug on a schedule, take the miss dose as soon as you remember or skip it if your next dose is approaching soon. You should never double up on dosages to make up for a missed dose.

What should I avoid while using this medication?

Avoid drinking alcohol or using aspirin during the time of treatment. Doing so may cause adverse interactions or unwanted side effects.

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