Do not use Norpramin (desipramine)
Norpramin should not be used by anyone who has ever had an allergic reaction to desipramine.
Those who have recently had a heart attack are not approved to use Norpramin.
A dangerous drug interaction could occur if you take Norpramin within 14 days of using an MAO inhibitor. Do not use Norpramin if you have used a MAO such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, or others in the past 14 days.
This drug can harm a nursing infant if used by a breast feeding mother. Do not use this medication if you are breast feeding an infant.
Do not use Norpramin if you are under the age of 18 years old.
Dose adjustment or special precautions may be required
To determine if Norpramin is right for you, tell your doctor if you have bipolar disorder, schizophrenia, a history of mental illness or psychosis, liver disease, heart disease, a family history of sudden death related to a heart rhythm disorder, a history of heart attack, stroke, or seizures, a thyroid disorder, diabetes, glaucoma, or problems with urination.
Risks
The risk of suicidal thoughts is increased in younger patients when taking an antidepressant for the first time. Caregivers of adolescents should carefully monitor any changes in mood or symptoms.
Tell your doctor if you are pregnant or plan on becoming pregnant; it is not known if this medication will harm an unborn baby.
An overdose on this medication can be fatal.