Nizoral (Ketoconazole)

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What is Nizoral used for?

A fungal infection, also called mycosis, is a skin disease caused by a fungus. There are literally millions of species of bacteria. They live in the dirt, on plants, on household surfaces and even on your skin. And sometimes it can lead to skin problems like rashes or bumps.

This medication is used to treat various but serious fungal infections in the body. It belongs to a class of drugs known as azole antifungals. This medication functions but putting a stop to the fungus’ growth.

While it does stop fungus infections, this medication should not be used on the skin and nails due to the risk of some very serious side effects and various drug interactions. If you would like more information regarding what medications you can and cannot take with Nizoral, speak with your doctor on the matter.

This medication is to be taken by mouth, and usually only once a day, and with or without food.  However, taking it with food does help with any issues of a upset stomach that may occur.

If you are taking an antacid, make sure to take it at least 2 hours before or 1 hour after taking the antacid. Otherwise the Nizoral may not be absorbed into the body.

Remember the dosage and length of the treatment is based on your medical condition, other medications you may be taking, and your overall response to the treatment. Make sure you speak with your doctor and let them know of all the medications you are taking, including prescription drugs, non-prescription drugs, and herbal products.

This medication works at its best when the amount of medicine in your body is kept at a constant level. Therefore you should be taking this medication at evenly spaced intervals. Perhaps it is best to take it at the same time each day. Do not stop taking this medication, discontinuing this medication so suddenly may result in various side effects and as a result, a return of the infection.

Before taking this medication, it is best to advise your doctor if you are allergic Ketoconazole; or to other azole antifungal drugs (such as fluconazole, itraconazole); or to any other medications or allergies in general. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Before taking this medication, it is for the best to inform your doctor of your Medical history. Especially if you have had any of the following; liver problems, alcohol use, low testosterone levels, decreased adrenal gland function problems (such as low cortisol levels, Addison's disease, adrenal insufficiency), little or no stomach acid production (achlorhydria).

Ketoconazole may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using ketoconazole, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using ketoconazole safely.

While minor, some of these side effects may occur. They are as follows; Nausea and vomiting may occur. However if any of these persist or worsen, it’s best to speak with your doctor right away.

Tell your doctor right away if any of these unlikely but serious side effects occur: headache, vision changes, mental/mood changes (such as depression, thoughts of suicide).

Although highly unlikely, when used in high doses, this medication may cause an adrenal gland problem, a decrease in testosterone levels and a decrease in sperm production. It may also worsen any existing adrenal gland function problems.

Get medical help right away if any of these rare but serious side effects occur: fast/irregular heartbeat, severe dizziness, fainting.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

What happens if I suddenly stop taking this medication?

There may be a relapse in symptoms as well as side effects. You should speak your doctor before stop taking this medication.

 

 What is the best dosage to take?

The diagnosis with your doctor will be able to determine the best dosage for your treatment. Work with your doctor closely for dosage and dosing schedules.

 

 What happens if I miss a dose?

You should take the missed dose as soon you realize you have forgotten. If the forgotten dose is closer to your next scheduled dose, take the next schedule dose to avoid overlapping in dose.

 

 What is the best way to store this medication?

This medication is stored at room temperature, and should be kept away from children and pets. Do not throw away this medication in the wastebasket. If you are uncertain how to dispose of this medication speak with your pharmacist for help in safely disposing of this medication.

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