Do not use Kaletra (Lopinavir/Ritonavir)
You should find an alternative medication if you have ever had an severe allergic reaction to lopinavir or ritonavir.
Dose adjustment or special precautions may be required
If you take medications such as alfuzosin; colchicine; dronedarone; elbasvir/grazoprevir; lurasidone, pimozide; ranolazine; rifampin; lovastatin, simvastatin; midazolam (oral syrup), triazolam; sildenafil (Revatio for pulmonary arterial hypertension); St. John's wort; or an ergot medicine (ergotamine, dihydroergotamine, methylergonovine) you may need a dose adjustment; consult your doctor if you use any of these medications.
If you have ever had liver disease (especially hepatitis B or C), heart disease, heart rhythm disorder, or a family history of long QT syndrome, pancreas problems, diabetes, low levels of potassium in the blood, or a bleeding disorder (like hemophilia) you may need to take special precautions when using this medication; consult your doctor if you have ever had any of these conditions.
Risks
This medication has potential to cause a serious heart problem; this risk is raised if you use certain medications at the same time. Tell your doctor about all medications you use. Call your doctor if you experience a headache with chest pain, fast or pounding heartbeats, and severe dizziness.
It is not known if this drug will harm an unborn baby if used by an expecting mother, however, HIV can be passed to your baby if your HIV is not properly controlled at the time of birth. Take all your HIV medication exactly as directed by your doctor.
Kaletra can affect birth control and cause it to become less effective; to avoid this, use a non-hormone method such as condoms or spermicide.
Women with HIV should not breast feed infants as the virus can be passed through breast milk.
This medication is not for us in newborn babies who are less than 14 days old (2 weeks). Premature babies should not receive treatment until 14 days after their original due date.