Prescription Icon Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.


Jentadueto is an oral tablet made up of an antidiabetic combination of linagliptin and metformin. We carry the brand choice of this medication in 2.5mg/1000mg.

Jentadueto is used in combination with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Untreated high blood sugar can cause kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems which can all be prevented with the use of Jentadueto. Not only does it help to prevent those conditions from occurring but it can also prevent more fatal consequences of high blood sugar such as heart attack or stroke. Diabetes type 1 cannot be treated with Jentadueto.

Jentadueto is effective in the treatment of high blood sugar in diabetes type 2 patients because of the abilities of linagliptin and metformin. Linagliptin helps by increasing the levels of incretins, a natural substance that helps to control blood sugar by escalating the release of insulin (especially after a meal). Incretins also decrease the amount of glucose (sugar) your liver makes. Metformin helps by allowing your body to respond properly the production of insulin in the body while also decreasing the amount of sugar made by the liver which would be absorbed by the stomach and intestines.

Take this medication exactly the way your doctor has directed you too. You may find the instructions on your prescription bottle if you forget.

You should be taking Jentadueto with a meal, twice a day.

Before starting treatment, ensure all members of the house hold know how to use the glucagon injection kit (if your doctor prescribed on along with Jentadueto).

Ensure you are following the diet and exercise portion of the treatment to allow Jentadueto to be effective.

Store Jentadueto at room temperature, protected from moisture and heat.


Before starting treatment, tell your doctor about all past medical conditions as well as all medications you are currently taking including prescription, over the counter, herbal supplements and vitamins, to determine if this medication is right for you.

Do not use Jentadueto (Linagliptin/Metformin)

You will need to find an alternate medication if you have severe kidney disease or if you have diabetic ketoacidosis.

If you are under the age of 18 years old, Jentadueto has not been approved for you use; do not use this product.

Dose adjustment or special precautions may be required

Mention to your doctor if you have liver disease, a serious infection, heart disease, a history of pancreatitis, if you recently had a heart attack, or if you are a senior over 65 years old and have not had your kidney function checked recently.

You should also mention to your doctor if you have had gallstones or high triglycerides, or if you have ever been an alcoholic.


When you use Jentadueto, you may have an increase risk of lactic acidosis. This is a dangerous build up of lactic acid in the blood. If you notice signs of lactic acidosis (see side effects), contact your doctor right away.

Using this product may cause easier fertility in woman; use effective birth control during the time of treatment if you are avoiding pregnancy.

Other cautions

You may need to temporarily discontinue use of Jentadueto if you need surgery or any type of x-ray or CT scan using a dye that has to be injected into your veins.

If you are pregnant or breast feeding; consult your doctor and follow directions very carefully. Having your blood sugar under control during pregnancy is very important and your doses may need to be changed during each trimester of pregnancy and while breastfeeding.

Side Effects

Common side effects of Jentadueto (Linagliptin/Metformin) may include:

  • sore throat,
  • sinus pain, stuffy nose, or
  • diarrhea.

The above side effects should not alarm you.

Serious side effects of Jentadueto (Linagliptin/Metformin) may include:

severe or ongoing pain in your joints.

If you have any of the above side effects, contact your doctor right away.

Contact your doctor if you notice signs of…

pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.

lactic acidosis: unusual muscle pain, feeling cold, trouble breathing, feeling dizzy, light-headed, tired, or very weak, stomach pain, vomiting, or slow or irregular heart rate.

heart failure: shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.

a severe autoimmune reaction: itching, blisters, breakdown of the outer layer of skin.

hyperglycemia: very hungry, dizzy, irritable, confused, anxious, or shaky.


Can I drink alcohol while using Jentadueto?

No. Do not drink alcohol while on Jentadueto. Doing so could increase your chance of lactic acidosis, which can be a fatal condition.

What should I do if I suspect an overdose?

If you suspect an overdose (symptoms similar to low blood sugar; extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure), call emergency service right away and eat or drink a fast-acting source of sugar in case it is actually severe hypoglycemia.

What type of diet is usually suggested during the treatment of Jentadueto?

Your diet should consist of (unless your doctor says otherwise) food like fatty fish (like salmon, sardines, and herring), leafy green vegetables (like spinach, kale and cabbage), cinnamon (like adding it into yogurt), eggs, chia seeds, turmeric, Greek yogurt, nuts (almonds, cashews, hazelnuts, macadamia, pecans), and broccoli. There are more foods that are good to eat when battling diabetes; consult your doctor for more.

Is this product safe for children?

This medication has not been approved for the use of children. If you are under the age of 18 years old, you are not approved to use this medication.

Call To Complete

Need Help?
Call Our CareTeam


Our CareTeam Member will guide you to complete your order