You may need to find an alternative medication or take special precautions when taking Inspra if you have high potassium levels in your blood (hyperkalemia), severe kidney disease, or type 2 diabetes with increased levels of albumin (a protein) in your urine. Consult your doctor if these conditions apply to you.
You are likely able to use Inspra, but may still need special precautionary measures or a dose adjustment before starting treatment if you have kidney disease, diabetes, liver disease, or if you have high cholesterol or triglycerides.
Your doctor may decide to change your treatment plan if you use certain types of medications. These medications include other medications for heart or blood pressure conditions, nefazodone, a potassium supplement, an antibiotic--clarithromycin, telithromycin, antifungal medicine--itraconazole, ketoconazole, a diuretic or "water pill"--amiloride, spironolactone, triamterene, or antiviral medicine to treat HIV/AIDS--indinavir, nelfinavir, ritonavir, saquinavir. Consult your doctor if you take any of these medications.
Tell your doctor if you are breast feeding or if you are pregnant. It is unknown if this drug passes into breast milk or if it will harm an unborn baby. However, having high blood pressure during a pregnancy can cause the baby to develop complications such as diabetes or extremely high blood pressure that can affect both the baby and mother poorly. Heart failure can worsen during pregnancy and cause the baby to be pre-mature (born early) which can also present complications in the newborn. The benefit of treating hypertension or heart failure may outweigh the risks to the baby.
Taking Inspra may cause partial or total infertility in men.