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Hygroton is an oral tablet made up of a diuretic/water pill called chlorthalidone. We carry the generic alternative to this medication in 50mg!

Hygroton is prescribed to treat high blood pressure, also known as hypertension. Untreated hypertension can cause strokes, heart attacks, and kidney problems. Blood pressure readings consist of two numbers, the systolic (first/top number) and the diastolic (second/bottom number). Normal blood pressure is 120/80, elevated blood pressure is 120-129/< 80 (less than 80), stage 1 high blood pressure is 130-139/80-89, stage 2 high blood pressure is 140+/90+ and a hypertension crisis is 180+/120+.

Hygroton (chlorthalidone) is effective in the treatment of high blood pressure because of its ability to decrease the amount of salt and water in the body to help decrease swelling and breathing problems caused by extra fluid in the lungs. It decreases the amount of salt and water by causing frequent urination. When there is less fluid in the body, the blood pressure goes down. It also helps by relaxing the blood vessels so that blood can flow more smoothly.

Always take prescribed medication the way your doctor has directed you to. This is important in order to avoid adverse interactions, unwanted side effects and ineffectiveness in treatment.

Take Hygroton by mouth with food, usually once a day (taken in the morning). It is best taken in the morning because if you take it too close to bedtime, you may find yourself up in the middle of the night having to urinate often.

Use this medication regularly to get the most benefit from it. Ensure you do not miss a dose by taking the tablet at the same time every day. You may also use a pillbox to help remind yourself to take the tablet.

Your dose will be based on your medical condition and response to treatment.


Before proceeding with the use of Hygroton, tell your doctor about all drug allergies you may have. This product may contain inactive ingredients, which can cause allergic reactions in some.

Tell your doctor about your medical history, more importantly, if you have ever had or have kidney disease, liver disease, gout, lupus, or an untreated mineral imbalance such as low potassium.

Be aware of the side effects this drug may cause. Do not drug or do other activities that require you to be fully alert until you understand the affect this drug has on you.

Be sure to stay hydrated while using this medication. Sweating, diarrhea, or vomiting an excess amount may cause you to lose too much body water, also known as dehydration, and may increase unwanted side effects. Limit alcohol beverages and tell your doctor if you are a daily marijuana user.

 Tell your doctor before having surgery about all the medications you are currently taking.

Chlorthalidone may cause a potassium deficiency. Ask your doctor about starting a potassium supplement or tips for a potassium rich diet while using this medication.

You may become more sensitive to the sun during the time of treatment. Wear sun protective clothing and accessories (like hats) and reapply sunscreen if you are in the sun for a prolonged time. Avoid the use of tanning beds.

This drug should only be used during pregnancy if the benefit outweighs the risk. Do not breast feed while on this medication; this drug passes into breast milk.

Side Effects

Common side effects of Hygroton (chlorthalidone) may include:

low blood levels of potassium which can cause muscle weakness, muscle twitching or abnormal heartbeat increased blood levels of uric acid increased blood levels of cholesterol.

The above side effects should not alarm you.

Serious side effects of Hygroton (chlorthalidone) may include:

abnormal heartbeat the symptoms of which include palpitations and fainting pins and needles headache feeling or being sick stomach pain constipation

If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

potassium deficiency: weakness and fatigue; muscle cramps, spasms, aches, or stiffness; digestive issues; heart palpations; tingling and numbness; or breathing difficulties.


What is the average dose for an adult with high blood pressure?

The initial dose for an adult with hypertension is 25mg once a day. Your doctor may eventually increase the dose to 50mg once a day.

Is this product safe for kids?

The safety and effectiveness of chlorthalidone (Hygroton) has not yet been established in pediatric patients.

How should I store this medication?

Keep your medicine in the original container it came in, stored in a cool dry place under 30 degrees Celsius. Protect from children and pets.

What are some medications that interact with Hygroton?

Other drugs that will affect Hygroton include other medications for high blood pressure or heart issues such as ACE inhibitors, beta blockers, methyldopa, vasodilators, calcium channel blockers, guanethidine, corticosteroids among others.

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