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What is Hydrodiuril?

Hydrodiuril is an oral tablet containing a thiazide diuretic called hydrochlorothiazide. We carry the generic alternative to this medication in 12.5mg, 25mg, and 50mg!

What is Hydrodiurl used for, and how does it work?

Hydrodiuril is a high blood pressure medication used to lower blood pressure. Uncontrolled hypertension (high blood pressure) can lead to a number of complications, including heart attack or stroke, aneurysm, heart failure, dementia, metabolic syndrome and more. Hydrodiuril not only helps to reduce these risks but also allows the patient to have an increased quality of life. Patients with edema caused by congestive heart failure, cirrhosis of the liver, kidney disorders, or taking steroids or estrogen may also take Hydrodiuril to help treat fluid retention (edema; excess fluid in the body).

Hydrochlorothiazide/Hydrodiuril is effective in treating both high blood pressure and edema because of its power to prevent your body from absorbing too much salt, which can cause fluid retention and increase the frequency of urinating. Your kidneys help control your blood pressure depending on the amount of fluid in your body. The more fluid, the higher the blood pressure, so by reducing the amount of liquid in the body, you are also lowering blood pressure.

Always follow directions given to you by your doctor. Instructions can usually also be found on the prescription or prescription bottle/container.

This medication is most commonly taken once a day, in the morning. You may take this medication with or without food, however directed by your doctor.

You may want to take this medication at least 4 hours before bedtime as you may find yourself waking up throughout the night to urinate.

High blood pressure usually has little to no symptoms; do not stop taking this medication even if you think you are better.


If you have difficulties with urinating, you will need to get that condition treated before continuing with Hydrodiuril.

Tell your doctor if you have liver or kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you have an allergy to sulfa drugs or penicillin in order to determine if this medication is safe or effective for you.

Avoid becoming overheated or dehydrated while doing physical activities such as sports or exercising. Keep in mind drinking too much can be just as bad as not drinking enough.

The list of drugs that interact with hydrochlorothiazide is very long; with your doctor, go over all the medications you are currently taking and any drug allergies you may have.

This medication is not expected to harm an unborn baby. However, other complications may occur, such as the baby developing jaundice. Tell your doctor if you are pregnant or plan on becoming pregnant.

This drug can pass into breast milk and can harm a nursing infant. Do not breastfeed while using this medication.

Side Effects

Common side effects of Hydrodiuril (hydrochlorothiazide) may include:

nausea, vomiting, loss of appetite; diarrhea, constipation; muscle spasm; or dizziness, headache.

The above side effects should not alarm you.

Serious side effects of Hydrodiuril (hydrochlorothiazide) may include:

a light-headed feeling, like you might pass out; eye pain, vision problems; jaundice (yellowing of the skin or eyes); pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum); shortness of breath, wheezing, cough with foamy mucus, chest pain; If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

Signs of electrolyte imbalance--dry mouth, thirst, drowsiness, lack of energy, restlessness, muscle pain or weakness, fast heart rate, nausea and vomiting, little or no urine; or

Severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.


What are the signs of an overdose?

Signs of overdose may include nausea, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness. Call emergency services right away if you expect an overdose.

What should I do if I miss a dose?

Take the missed dose as soon as you remember if your next dose isn’t already approaching; if the next dose is soon, skip the missed dose. Do not double up on medicine to make up for a missed dose.

Is this medication approved for children's use?

No. This medication has not been approved for those under 18 years old.

What other medication will affect Hydrodiuril?

Other medications that may affect Hydrodiuril include, but are not limited to, cholestyramine, colestipol; insulin or oral diabetes medicine; lithium; other blood pressure medications; steroid medicine; or NSAIDs like aspirin, ibuprofen, and naproxen.

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