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Hiprex is a urinary antibiotic tablet made up of methenamine hippurate. We carry both the brand choice and generic alternative in 1g.

Hiprex is used to prevent bladder infections in people who are prone to them (get them often). Typically Hiprex is given after other antibiotics have treated the initial infection because Hiprex will only help kill the bacteria (cause of the infection) but won’t chemically help the infection to heal. Bladder infections are usually painful and can be caused from bacteria by frequent sexual intercourse, sexual intercourse with a new partner, diabetes, or having a recent bladder or kidney infection.

This medication is effective in the treatment of bladder infections due to its contents containing an ingredient that allows the urine to become more acidic, allowing a chemical change (methenamine turns into formaldehyde), killing the bacteria in the urine.

Re-read all the directions on your prescription label before proceeding to take Hiprex; follow your doctor’s instructions very carefully. Taking more of a dose than prescribed will not help heal your condition faster but could worsen the unwanted side effects.

This medication is taken by mouth, regularly (daily).

If giving this medication to a child, you may have to break the tablet in half; consult your doctor if you are unsure how much to give your child.

Drink plenty of water during the duration of treatment. Your doctor may suggest drinking drinks such as cranberry juice, to help make your urine more acidic.  They may ask you to avoid dairy products.

If you symptoms improve quickly, do not stop taking the medication. Continue taking the medication for the entire prescribed time/amount.

Store at room temperature away from moisture, heat and light. Keep the bottle tightly closed when you are not using it.


Certain diseases and conditions may interact with Hiprex or cause a contradiction. If you are a person with severe liver disease or kidney disease, your doctor will likely suggest you find an alternative medication. This medication may not be safe for you to take. Consult your doctor for more information.

You may also need to find an alternative medication if you are currently taking a sulfa drug or are dehydrated. You may find yourself experiencing serious side effects, ineffectiveness or adverse interactions.

Other conditions, even if they are no longer an issue, may not be the greatest to mix with methenamine hippurate; however a dose adjustment or special cautions can be made to allow for an effective and safe treatment using Hiprex. Speak with your doctor if you have or had liver disease, asthma, an allergy to aspirin, or an allergy to yellow food dye.

Hiprex has potential to harm an unborn baby when taken during the first half of pregnancy. It is unknown if it will harm a baby in the final months of pregnancy. Tell your doctor if you are pregnant or plan on becoming pregnant.

Consult your doctor if you are breast feeding.

Side Effects

Common side effects of Hiprex (methenamine hippurate) may include:

painful or difficult urination; upset stomach, nausea; or rash.

The above side effects should not alarm you.

Serious side effects of Hiprex (methenamine hippurate) may include:

painful urination; increased urination; blood in the urine; or any new or worsening symptom.

If you have any of the above side effects, contact your doctor right away.


What is Hiprex?

This medication is used to prevent and control any returning urinary tract infections caused by bacteria. It is not meant to be used on just any kind of active infection. This medication is solely used stop the growth of bacteria in the urine. Hiprex also contains an ingredient that helps to make the urine acidic. When the urine is acidic, methenamine turns into formaldehyde to kill the bacteria. This medication comes in a singular dose of 1g. If you have any questions regarding this medication or any inquiries in general, feel free to give us a call at our toll-free number 1-877-385-8998.

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