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Known as Fosavance internationally


Fosamax Plus D is an oral tablet made up of a combination of a bisphosphonate drug called alendronate and a form of vitamin D called colecalciferol. Fosamax Plus D is also known as Fosavance internationally and can purchased in 70mg/2800iu and 70mg/5600iu!

Fosamax is prescribed to adults to treat and prevent osteoporosis. Osteoporosis is a bone disease where the body either loses to much bone, makes too little bone or a combination of the two. Fosamax Plus D is also prescribed to those who suffer from Pagets disease of bone. Pagets disease is when the bones become deformed from structural changes and causes the bones to weaken.

Fosamax Plus D (alendronat/colecalciferol) is effective in the treatment of osteoporosis due to its ability to alter the bone formation and breakdown in the body, which helps to slow the progress of bone loss and may assist with the prevention of bone fractures. Colecalciferol is also effective as it is a form of vitamin D which helps assist with the production of healthy bones and absorption of calcium from the stomach.

Your doctor will tell you before prescribing you Fosamax Plus D (alendronate/colecalciferol) exactly how to take this medication. Follow his or her directions, they can usually be found on the prescription label if you forget.

Fosamax Plus D should be taken in the morning when you get up, (30 min) before your first meal of the day. This medication is only needed to be taken once a week. Choose what day of the week you’d like to take you pill and continue taking it on the same day of every week. Ensure the tablet is swallowed whole and taken with a full glass of water.

Stay upright for the next 30 minutes; you may stand, sit, and walk but avoid lying down. If you take calcium or iron supplements, vitamins, antacids, coffee, tea, soda, mineral water, calcium-enriched juices and food, ensure you are taking Fosama Plus D  at least 30 minutes before; ideally wait 1 – 2 hours in between. Taking these substances at the same time as Fosamax Plus D  may cause absorption of the drug to decrease. Take this medication regularly to get the most benefit from it.


If you have problems in your esophagus or low levels of calcium in your blood, avoid using Fosamax Plus D. Using this product could cause your condition to worsen.

It is rare however; there have been cases where Fosamax Plus D causes bone loss in the jaw or femur fraction (broken leg). Monitor yourself for the signs of bone loss; go to side effects for warning signs.

You need to mention to your doctor if you have trouble swallowing, problems with digestion or other stomach issues, dental problems, kidney disease, or any kind of condition that causes malabsorption (issues absorbing nutrients), in order to determine if Fosamax Plus D is safe for you.

It has not been established if alendronate will harm an unborn baby in a pregnant woman nor has it been established if it passes into breast milk. Consult with your doctor about the benefits and risks before proceeding to use this medication if you are pregnant or breast feeding.

Side Effects

Common side effects of Fosamax Plus D (alendronate/colecalciferol) may include:

mild heartburn, stomach upset; diarrhea, gas, constipation; mild joint or back pain; or headache.

The above side effects should not alarm you.

Serious side effects of Fosamax Plus D (alendronate/colecalciferol) may include:

chest pain, new or worsening heartburn; difficulty or pain when swallowing; pain or burning under the ribs or in the back; new or worsening heartburn; severe joint, bone, or muscle pain; new or unusual pain in your thigh or hip; or jaw pain, numbness, or swelling.

If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

low calcium levels - muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).

bone loss in the jaw - jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work.

femur fracture – leg or groin pain

Stop using this medication and call your doctor right away if you have warning signs of low calcium, bone loss, or a femur fracture.


What is the main difference between Fosamax and Fosamax Plus D?

Fosamax and Fosamax Plus D are more similar than not, however, Fosamax Plus D has a form of vitamin D called colecalciferol. Fosamax only has one active ingredient, which it shares with Fosamax Plus D which is alendronate. Fosamax has a generic alternative however Fosamax Plus D does not at this time.

Does this medication help with bone mass production?

Yes it does! Fosamax Plus D is effective in increasing bone mass.

What is the average dose for a man trying to increase bone mass?

To increase bone mass: take once 70mg/5600iu once a week.

What if I miss a dose?

Take the missed dose the morning after you remember. Do not take more than two tablets in a day. Continue taking your next dose on the next scheduled dose day.

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