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Florinef is an oral tablet made up of a steroid (mineralocorticoids) called fludrocortisone. Mineralocorticoids are a man-made form of glucocorticoids, a natural steroid produced in the human body.  We carry the brand choice of this medication in 0.1mg!

Florinef (fludrocortisone) is a medication often times prescribed along with other medications to patients who do not produce enough of their own natural steroids and have a low glucocorticoid level due to certain diseases of the adrenal gland. Some of these conditions include Addison's disease, adrenocortical insufficiency, and salt-losing adrenogenital syndrome. A person who does not naturally produce enough glucocorticoids may find a disturbance in salt and water levels and blood pressure.

This medication is effective in the treatment of insufficient glucocorticoid levels as fludrocortisone is able to reduce the inflammation in the body.

Always follow directions given to you by your doctor. Most prescription labels have the directions written on them for your convenience. If you’re unsure on how to take this medication, contact a healthcare professional.

You may take Florinef once a day, with or without food.

Use this medication regularly to get the most benefit from it. Take this tablet at the same time every day to ensure you do not miss a dose. Do not increase or decrease your dose unless directed to by a doctor.


Tell your doctor about all medical conditions and medications you are currently taking including prescription, over-the-counter, vitamins, and herbal remedies. Also be sure to mention any drug allergies you may have.

If you are a person who has a fungal infection (e.g. athletes foot; ringworm) or if you are a person with an allergy to fludrocortisone, you should avoid using this product. The risks likely outweigh the benefits, however you may speak to your doctor and he can determine if this product can be made safe for you.

This product has been known to weaken the immune system, allowing infections to grow or spread more easily. Be cautious when around ill or infected people while using Florinef.

You may need to take special precautions when using Florinef or may need a dose adjustment if you have a condition that could interact with the contents of Florinef. To determine if Florinef is the right medication for you, be sure to tell your doctor if you have diabetes, kidney disease, osteoporosis, myasthenia gravis, a stomach ulcer, a thyroid disorder, tuberculosis (or if have daily contact with a person with tuberculosis), heart problems, high blood pressure, glaucoma, cataracts, herpes of the eyes, ulcerative colitis, diverticulitis, a colostomy or ileostomy, cirrhosis or other liver disease, mental illness or psychosis.

Using this product during the duration of pregnancy could cause the baby to develop adrenal gland problems. Speak with your doctor about using this medication when pregnant to learn more about the risks.

It may not be safe to breastfeed while using Florinef; avoid breastfeeding until you’ve talked to your doctor.

Side Effects

Common side effects of Florinef (fludrocortisone) may include:

increased blood pressure; stomach pain, bloating; facial redness; acne, increased sweating; sleep problems (insomnia); pitting, scars, or bumps under your skin; stretch marks; or increased hair growth of body hair.

The above side effects should not alarm you.

Serious side effects of Florinef (fludrocortisone) may include:

swelling of feet or lower legs, rapid weight gain; muscle weakness, loss of muscle mass; blurred vision, tunnel vision, eye pain, or seeing halos around lights; bloody or tarry stools, coughing up blood; unusual changes in mood or behavior; or a seizure;

If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;

pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting; or

increased adrenal gland hormones--weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Call your doctor at once if you notice any of the signs above.


What other medications will interact with this medication?

Discuss with your doctor about all the different drug interactions. Some drug interactions may include aspirin, diuretics, insulin, birth control pills, and blood thinners.

Is this product safe for the use in children?

No. Florinef has not been approved for use in those under the age of 18 years old.

What should I avoid while using Florinef?

While using Florinef, you will want to avoid people who are sick or have infections as your immune system may weaken during the duration of treatment.

What is the average dose for an adult with Addison’s disease?

The average dose for an adult with Addison’s disease would start off on 0.1mg once a day. The maintenance dose would be 0.2mg once a day or 0.1mg three times a week.

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