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Known internationally as Oestrogel

What is Estrogel?

Estrogel contains estradiol. It is a prescription medication used to improve symptoms of menopause. Estrogel may be prescribed alongside other medications to improve menopause treatment results. This medication belongs to the drug class of estrogen derivatives. Estrogel is a type of hormone replacement therapy and comes with certain risks. Estrogel, either used alone or with progestin, should not be used to prevent cardiovascular disease or dementia. Speak to your doctor about whether Estrogel is right for you.

Estrogel Uses

Estradiol is a white powder that is clear, colorless, and odorless when it is dry. Estrogel contains 0.06 percent estradiol mixed with a gel base. It is used to treat moderate to severe vasomotor symptoms (symptoms related to the constriction or dilation of the blood vessels) that occurs during menopause. Estrogel is also used to treat moderate to severe vulvar and vaginal atrophy caused by menopause. Estrogel should not be prescribed for postmenopausal women with a uterus as doing so increases the risk of endometrial cancer. Prescribing Estrogel with progestin may reduce this risk.

Generic Estrogel has not been approved yet in the United States. Many fraudulent online pharmacies may claim to sell generic Estrogel, but these sources are likely distributing counterfeit versions that may put your health at risk. Usually, generic drugs offer an affordable option without sacrificing effectiveness. As there is no generic Estrogel at this point, the cheapest option to fill your prescription will be through an online Canadian pharmacy like My Drug Center.

Estrogel Price

As mentioned above, generic Estrogel is not available, so saving by going the generic route is not an option. In the future, a generic version of Estrogel may be developed and approved. In the meantime, the best way to save on brand-name Estrogel is through an online pharmacy that sources medications from Canada.

Buying Estrogel Online

Buying Estrogel online through a Canadian pharmacy has many advantages. For example, an online pharmacy helps you save time since you will not have to line up at your local pharmacy ever again. From a cost-effectiveness perspective, filling your prescription online is also beneficial. My Drug Center brings you affordable brand-name Estrogel so you can focus on getting better.

Estrogel from Canada

Estrogel from My Drug Center is significantly more affordable because we source your medication from many countries outside the U.S. Countries like Canada have regulations that keep the price of drugs low. By getting Estrogel from Canada, you join thousands of Americans in saving on their prescription medications from the comfort of home.

Estrogel Side Effects

Common side effects of Estrogel (estradiol) may include:

  • Breast pain
  • Headache
  • Vaginal itching
  • Vaginal discharge
  • Changes in your menstrual periods
  • Thinning hair
  • Nausea, vomiting, stomach cramps, or bloating

Although the above side effects can be expected, watch out for severe side effects that require a doctor's attention. Severe side effects may include:

  • Heart attack
  • Liver problems
  • Stroke
  • Blood clots in the lungs or the legs

If any of these side effects occur, seek medical help immediately.


Estrogel will not be effective in preventing heart disease, heart attack, stroke, breast cancer, or dementia. Using Estrogel may increase the chance of these conditions as well as increase your risk of uterine or ovarian cancer. Ask your doctor about what your risk is for developing these conditions.

Certain diseases and conditions will interact with Estrogel, and you should avoid using this product if you have any of the following conditions:

  • Abnormal vaginal bleeding
  • Breast, uterine, or hormone cancer
  • A history of heart attack, stroke, or blood clots
  • Liver disease
  • An estradiol allergy
  • Estrogel and Pregnancy

This product should not be used during pregnancy; ensure you are using appropriate birth control methods during the time you are on Estrogel. This medication can pass into breast milk, so avoid breastfeeding while on Estrogel if possible.


What should I avoid if I am using Estrogel?

Research shows that you may want to avoid applying sunscreen the same time you adminsiter Estrogel. Avoid getting estradiol in the eyes or mouth. Estrogel may interact with certain foods, such as grapefruits. Ask your doctor about other things to avoid while on this medication.

How long does it take for Estrogel to work?

Generally, it takes up to four months for patients to feel the beneficial effects of Estrogel. Every patient is different, and you may begin experiencing improvements in symptoms much sooner.

How should I store this medication?

Store Estrogel away from heat and moisture. It is recommended to store this medication at room temperature.

Is Estrogel safe for children?

No. Do not let children come in contact with Estrogel. This medication is a type of hormone replacement therapy and is not approved for use by children.

Where should I apply Estrogel?

This product is usually applyed on the inside and outside of your arm from your shoulder down to your wrist. Avoid applying Estrogel directly to the breasts or the vagina.

What is the best time to apply Estrogel?

Whether you prefer to apply estradiol in the morning or the evening, it is a good idea to apply Estrogel at the same time each day. Apply Estrogel after showering so that you have clean and dry skin.

Does Estrogel cause weight gain?

There is no evidence to support that Estrogel contributes to weight gain. Weight gain during treatment with Estrogel may be caused by menopause. Exercising and eating healthily can help you maintain a healthy weight during treatment.

Does Estrogel change your appearance?

This varies from patient to patient, but Estrogel contains a type of estrogen that may cause skin changes on the face, especially around the eyes. Talk to your doctor for more information on hormone replacement therapy with Estrogel.

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