Prescription Icon Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.


Estrace is an oral tablet made up of an estrogen called estradiol. Estrace is a small round pill, usually white or blue in color and is available in both generic and brand choices! We carry this medication in 0.5mg 1mg and 2mg!

Estrace is most commonly prescribed to women going through menopause.. Menopause usually occurs in women older than 40 between the ages of 47 and 53 when a woman’s period is no longer active (ovaries stop making estrogen and progesterone). This medication can help treat the symptoms that come with menopause like hot flashes, vaginal changes and prevent bone loss (osteoporosis). Additionally, this medication can be used to replace estrogen in woman who cannot produce or cannot produce enough natural estrogen and for the partial treatment of cancer in both men and woman.

This medication works for these conditions as it replaces any loss estrogen and balances out the hormone levels.

Make sure to take this medication exactly the way your doctor tells you too. Do not take more or less of a dose than directed to.

You may take this tablet with food to avoid the chance of a stomachache. Avoid chewing or crushing these tablets.

Take this medication regularly to get the most benefits out of it.

Store at room temperature away from moisture, heat, and light and ensure the bottle is tightly closed when not in use.


This medication should not be used by anyone who:

has undiagnosed, unusual vaginal bleeding; liver disease; has a history of heart attacks, strokes, or blood clots; an increased risk of having blood clots due to a heart problem or a hereditary blood disorder; or a history of hormone-related cancer, breast, uterus/cervix, or vagina cancer.

You may need a dose adjustment or special instructions to follow if you have any of the following conditions; make sure to tell you doctor if you have:

heart disease; liver problems, or jaundice caused by pregnancy or taking hormones; kidney disease; gallbladder disease; asthma; epilepsy or other seizure disorder; migraines; lupus; endometriosis or uterine fibroid tumors; hereditary angioedema; porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); a thyroid disorder; or high levels of calcium in your blood.

This medication may increase the risk of blood clots; especially those who have high cholesterol, hypertension, diabetes, are overweight or a smoker.

Estrace should not be used to prevent conditions like heart disease, stroke, or dementia. The conditions may develop while using Estrace.

Breast, uterus, and ovary cancer all become a risk when you begin taking Estrace. Talk with your doctor if this risk concerns you.

Breast milk production may become slower when using Estrace. Mention to your doctor if you are breast feeding.

Side Effects

Common side effects of Estrace (Estradiol) may include:

nausea, vomiting, diarrhea, stomach cramps; mood changes, sleep problems (insomnia); cold symptoms such as stuffy nose, sinus pain, sore throat; weight gain; headache, back pain; breast pain; thinning scalp hair; or vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding.

The above side effects should not alarm you.

Serious side effects of Estrace (Estradiol) may include:

swelling or tenderness in your stomach; jaundice (yellowing of the skin or eyes); memory problems, confusion, unusual behavior; unusual vaginal bleeding, pelvic pain; or a lump in your breast

If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

high levels of calcium in your blood - nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, lack of energy.

heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.

signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.

signs of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs.


What should I avoid while on this medication?

While taking Estrace, you should avoid smoking. Smoking while on this medication may increase your chance of blood clots, stroke, or heart attack.

Are there any foods I should avoid?

Grapefruit and grapefruit juice may have an interaction with Estrace potentially leading to unwanted side effects. Avoid the use of grapefruit products.

What can I do to help Estrace reduce hot flashes?

To help reduce hot flashes, quit smoking (if you’re a smoker), dress lightly or in easily removable layers, avoid (or limit) things like caffeine, alcohol, and spicy foods, reduce stress levels and exercise often.

What should I do if a part of the tablet is in my stool?

This should not alarm you too much but it is something you should mention to your doctor when you see him or her next.

Call To Complete

Need Help?
Call Our CareTeam


Our CareTeam Member will guide you to complete your order