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Erythromycin Eye Ointment is a macrolide antibiotic ointment made up of erythromycin. This ointment can be purchased as 0.50% or as 5mg/g.

Erythromycin Eye Ointment is used to treat bacterial infections located in the eye as well as preventing certain eye infections in newborns. Some infections that erythromyxin helps to treat include trachoma, pink eye, conjunctivitis, blepharoconjunctivitis, and imflammation of the cornea or meibomian gland, among others.

This ointment works to fix these infections by stopping the growth of bacteria as bacteria is the main cause of these infections.

Make sure to follow the directions given to you by your doctor

To prevent the further spreading of bacteria, ensure you: wash your hands before and after each use; do not touch the tip of the ointment tube; do not touch your eye directly with the top of the tube.

Use this medication for the full prescribed amount, even if you feel your infection has healed. Stopping this treatment too soon can cause the infection to come back or allow for resistance (troubles treating the infection).

Store at room temperature away from moisture, heat and children.

How to apply ointment to the eye:

  • Tilt your head back
  • Look upward
  • Form a pouch by pulling down on your lower eye lid
  • Squeeze the tube gently to allow 1/3 of an inch (1-cm) strip of the ointment into the eye
  • Look down and gently close your eyes for 1 – 2 minutes
  • Roll your eye in circular motion to ensure medication is event spread into the eye


You should not use Erythromycin Eye Ointment if you are allergic to erythromycin, if you have a viral or fungal infection (you would need an antiviral or antifungal drug for these infections).

It may not be safe to breast feed while also using Erythromycin Eye Ointment. Discuss the benefits and risks with your doctor.

This medication has not be established as safe for a pregnant woman; this product may or may not cause harm to an unborn baby.

Tell your doctor you history with using contacts before using this ointment.

Your vision may become blurry after using this product. This will pass and should not alarm you.

Side Effects

Common side effects of Erythromycin Eye Ointment may include: eye redness or mild irritation

The above side effects should not alarm you.

Serious side effects of Erythromycin Eye Ointment may include: severe burning, stinging, or irritation

If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

eye infection--pain, swelling, severe discomfort, crusting or drainage, eyes more sensitive to light.

allergic reaction-- hives; difficult breathing; swelling of your face, lips, tongue, or throat.


What should I avoid when using this product?

Avoid driving after applying the ointment as sometimes vision may become blurred. Avoid driving until you know exactly how this medication affects you.

Can I use other eye medications while using this one?

Only if you have been directed to by your doctor, otherwise do not use a combination of eye medications at the same time.

What if I miss a dose?

Apply the missed dose as soon as you can unless your next dose is approaching; skip the missed dose and continue as normal. Do not use extra ointment to make up for a missed dose.

What does this medication look like?

This medication comes in a small tube and is usually white and yellow; appearances may vary based on if you buy generically or a brand choice.

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