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What is Efudex Cream used for?

Efudex Cream is a medication that is commonly prescribed as a treatment for basal cell carcinoma, the most common type of skin cancer worldwide. It may also be used to treat actinic or solar keratosis, a skin condition that may lead to skin cancer.

You can buy Efudex Cream online at My Drug Center. We have the Efudex Cream generic, called Flourouracil Cream, available for purchase as well.


How does Efudex Cream work?

Efudex Cream is a topical medication that contains the active ingredient Flourouracil, which belongs to the group of medicines known as antimetabolites. When applied to the skin, it is used to treat certain skin problems, including cancer or conditions that could become cancerous if not treated. The Fluorouracil dosage in the medication interferes with the growth of abnormal cells, which are eventually destroyed.

Before taking Efudex or the Flourouracil Cream generic, read all the instructions and paper work that given to you by your pharmacist. Take your Efudex Cream dosage orally once a day. Wash then dry the effected area. After roughly ten minutes use a small amount of the cream on the effected areas to create a thing layer. After applying the medication wash your hands right away.

Make sure you use it at the same time each day to create a routine for yourself and to ensure an even spread of the Flourouracil dosage in your system. This medication should be taken on a regular basis to have optimal results. The Efudex Cream dosage that you take will depend on your condition and your age. Use this medication exactly as prescribed by your doctor. Do not change or increase your dose. You should continue taking this medication even if you feel well.

The effected area can appear unattractive for a few weeks as the treatment begins. Do not cover the effected area unless instructed by your doctor.

Use this medication exactly how it is prescribed, and do not use more medication that required or stop unless instructed by your doctor.


Efudex Cream or the generic may contain medical and non medical ingredients that could cause an allergic reaction. Consult with your doctor about any known allergies before taking Efudex Cream. Speak with your doctor about any known medical conditions relating to enzyme deficiency. Be sure to discuss other medical conditions, known allergies, and list any over-the-counter or prescription medications, and herbal products you are currently taking.

Efudex Cream can cause you to be more sensitive to the sun. Limit sun exposure, tanning booths, and heat lamps. Wear protective clothing in the sun and wear sunscreen on unprotected areas to avoid discolorations n your skin. If you are applying sunscreen on any effected areas you should wait at least two hours before applying any protective cream. Avoid other skin products or cosmetics, lotions, or creams unless instructed by your doctor.

Side Effects

Efudex Cream side effects include:

Skin irritation, burning, redness, dryness, pain, swelling, tenderness, scaling, peeling (exfoliation), rash, changes in skin color at the site of application, or other local reactions, eye irritation, trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth.

Some serious Efudex Cream side effects include:

Stomach or abdominal pain, bloody diarrhea, vomiting, signs of infection (e.g., fever, chills, persistent sore throat), easy bruising or bleeding, or mouth sores.

If any side effects of Fluorouracil become unmanageable speak with your doctor or pharmacist for help in managing any side effects. For any serious side effects that occur speak with your doctor right away for further treatment options.


What is Fluorouracil?

Efudex is listed on Medicare’s Tier 2 of their formulary. Meaning this medication is a “non-preferred generic”.  This means Medicare covers a good majority of this medication, through Medicare Part D and Medicare Advantage plans. Fluorouracil is a topical cream, and it is used to treat pre-cancerous or cancerous skin growths. And it is put to work by blocking the growth of abnormal cells that cause the skin condition. Efudex only comes in the one strength of 5%. If you do have any questions, feel free to call us here at My Drug Center at 1-877-385-8998.


How to use Efudex cream?

Since this medication is a cream, it is to be used on the skin only. Before you begin, make sure to wash the affected are and pat it down dry. After a few minutes, apply a small amount to the affected are and then gently rub it in. Once done, wash your hands. Do not cover, wrap, or bandage the area unless told otherwise by your doctor. Just be sure to use this medication exactly as prescribed to you.


How long does it take for Fluorouracil Cream to work?

Usually it takes at least 3 to 6 weeks for the cream to start to take effect. However, it may also take 10 to 12 weeks. During the first few weeks, the skin lesions and the surrounding areas should feel irritated and look red, swollen and a bit scaly. This is actually a sign that this medication is working.


How much does Fluorouracil Cream cost?

While Efudex Cream can be affordable at your local pharmacy, you can buy this medication at an approved online Canadian Pharmacy as well, such as My Drug Center. Where there may be much more affordable options. Our starting price is at $63.00 for 40 grams.


What are the side effects of Fluorouracil 5% cream?

Some of the most common side effects to this medication are as follows; application side reactions (such as redness, dryness, burning, erosion, pain, irritation, and swelling.), headache, common cold, allergy, upper respiratory infection, muscle soreness, sinus infection, sun sensitivity, and eye irritation. Keep in mind that these are not all of the side effects listed for this medication. And if any of these effects persist or worsen, you should consult with your doctor.

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