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Known as Adaferin Gel internationally


What is Differin Gel(Adapalene) prescribed for?

Acne starts with greasy secretions of the skin’s oil glands plug the pores. Depending on the opening of the pore, the clog can take form of a blackhead or pimples. And while acne is mostly seen in youths, mostly teens, about 20% of adults still share the burden of acne.

This medication is used to treat acne, and in using it you may decrease the number and the severity of acne pimples and promote a quick healing for pimples that do develop. Overall, this medication functions by affected the growth of the cells and decreasing the swelling and inflammation.

This medication comes in a singular strength of 0.10%. Remember your dose is based on your medical background and your overall response to the treatment. If your doctor or pharmacist has given you some information in the form of a pamphlet, take the time to read up on this drug, and if you have any questions or concerns regarding this medication, please consult your doctor.

The gel should be applied to the affected areas of the skin, only once daily, and usually at nighttime. Wash your hands beforehand. And once the affected areas have been cleaned and dried, layer a thin film of gel on where the acne lesions appear.  Use enough to cover the entire affected areas lightly.  While apply you may feel a warmth and a slight stinging. This may occur shortly after you have applied this medication.

Use this medication on the skin only, do not make contact with the eyes, nose or mouth.  If this medication does get into the eyes, flush thoroughly, and call your doctor if an irritation persists.  

Make sure to follow your doctor’s instructions carefully. Use only what has been given to do and what has been prescribed to you.


Before taking this medication, inform your doctor if you are allergic to Adapalene; or to vitamin A-related drugs (other retinoids such as isotretinoin); or if you have any other allergies in general.

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Weather extremes such as wind or cold may also be irritating to the skin. Use sunscreen daily and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Wait until your skin has completely recovered from a sunburn before using adapalene.

Avoid electrolysis, waxing and chemical depilatories for hair removal on the treated areas while using this product.

If you have recently used products containing sulfur, resorcinol or salicylic acid, use adapalene with caution. Wait until the effects of such products on the skin have decreased before using adapalene.

Side Effects

A brief sensation of warmth or stinging may occur right after applying the medication. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use. If any of these effects lasts or gets worse, tell your doctor or pharmacist promptly. Your doctor may want you to decrease how often you use adapalene, change the strength, or have you stop using it.

There is some serious side effects to this medication, and if you are encountering any of them, notify your doctor right away. These side effects are listed below; very red/irritated skin, an intense burning sensation, eye redness and watering (conjunctivitis), eyelid swelling, skin discoloration.


What is Differin Gel?

Differin Gel is a topical medication with beneficial effects for a dermatological condition that causes inflammation of the face. It contains a drug belonging to the class of medications called retinoids. Differin Gel contains 0.10% of the retinoid and can be purchased as either the brand name or the generic alternative at My Drug Center.


What is in Differin Gel?

The active ingredient found inside Differin gel is called adapalene. It is the retinoid that gives Differin Gel its therapeutic effects. Differin Gel also contains inactive ingredients; this may include water, hydrochloric acid, sodium hydroxide, propylene glycol, poloxamer 182, methylparaben, edetate disodium, and carbomer homopolymer type C.


What is adapalene gel used for?

Adapalene gel, or Differin Gel, is used for the treatment of acne; what does Differin gel do for acne? It helps reduce both the frequency and severity of acne and encourages quicker healing for currently existing acne. Differin gel also has demonstrated noteworthy anti-inflammatory effects; this will help reduce inflammation (swelling and redness).


How to use Differin gel?

Do not begin treatment until you are sure you understand how to use the medication correctly as directed by your doctor. Use this medication on the skin only. Wash your hands as well as the affected area, drying thoroughly, before proceeding. Use a thin layer of gel to evenly cover the entire affected area. Avoid getting the medication in your eyes, nose, or mouth; rinse thoroughly with water if contact should occur.


Where to buy Differin gel?

You can buy Differin Gel online at My Drug Center. We supply Differin Gel in 30, 60, and 90 gram bottles in both the brand-name and generic option. How much is Differin gel at My Drug Center? Differin Gel can be found as low as $38.00 for a generic supply of a 30 gram bottle.


How long does Differin gel take to work?

The exact amount of time may vary between each individual depending on a number of factors. Commonly, improvement within the condition can be seen around 8-12 weeks of proper treatment.


What products to use with Differin Gel?

Some patients “buffer” the medication by using a separate moisturizer to help lessen irritation. Irritation commonly occurs during the first 4 weeks of treatment while your skin adjusts to using the retinoid. According to, these are some of the best moisturizers to use with Differin Gel:

For Oily Skin: CeraVe PM Facial Moisturizing Lotion

For Very Dry Skin: CeraVe Moisturizing Cream

For Combination Skin: Paula’s Choice Hydralight Moisture Infusing Lotion

For All Skin Types: Hadalabo Gokujun Hyaluronic Lotion

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