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Desowen Lotion is a topical, mild corticosteroid made up of desonide. We carry the brand name Desowen Lotion in 0.05% bottles.

This lotion is used for a variety of skin conditions. Some of these conditions include eczema, dermatitis, allergies and rashes. Eczema involves itchy, red and dry skin caused by inflammation which is similar to dermatitis, which is when the skin becomes red and tender but only when you touch certain things. Allergies are also similar to dermatitis, as allergies are caused by certain substances or foods; only allergies will cause symptoms like sneezing, nasal congestion, and wheezing as well as itchy eyes and skin. Rashes are similar to eczema as they are also are (commonly) caused by inflammation and result in a change in skin color or texture.

All of the listed conditions are quite similar in certain ways, and desonide is able to treat them by activating the natural substances in your skin that help to reduce inflammation and the following symptoms like redness and itching.

This medication was designed for skin use only; do not inhale, insert or digest this medication. In the case that you do accidently get this medication inside of you, rinse thoroughly with water.

Do not cover, wrap, or bandage the affected area after applying the lotion. If the affected area is in the diaper area on an infant, ensure you are not using a tight-fitting diaper.

1.       Shake the bottle well

2.       Wash your hands

3.       Clean and dry the affected area

4.       Apply a thing film of lotion; gently rub into skin

5.       Repeat 2-3 times a day or as directed by your doctor


Make sure to tell your doctor about all drug allergies you have, especially if you are allergic to desonide. Tell your doctor what allergy signs you noticed if you have had an allergic reaction to a medication in the past.

This medication should not be used on any sort of open wound, cut or damaged skin. Do not use this lotion on an area that has an infection; consult your doctor first.

Avoid putting this medication on any area of skin that is thinning; consult your doctor if this concerns you

Tell your doctor and pharmacist about all of your drugs including prescription, OTC, natural products, vitamins as well as health problems.

Do not start, stop, or change the dose unless you have been directed to by your doctor.

You will need to discuss the risks and benefits of this drug if you are currently pregnant or plan on becoming pregnant. This also applies if you are a breast feeding mother.

Avoid using this product for longer than your prescription says too.

Side Effects

Common side effects of Desowen Lotion (Desonide) may include:

  • Burning
  • Stinging
  • Dry skin
  • Signs of a common cold

The above side effects should not alarm you.

Serious side effects of Desowen Lotion (Desonide) may include:

  • Skin irritation
  • Skin changes (pimples, stretch marks, slow healing, hair growth)
  • Change in color of skin
  • Change in eyesight, eye pain, or very bad eye irritation

If you have any of the above side effects, contact your doctor right away.

Signs to watch for:

Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.

Signs of a weak adrenal gland like a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss.

Signs of Cushing's disease like weight gain in the upper back or belly, moon face, very bad headache, or slow healing.


Is it okay to share this lotion with someone else who has recently ran out?

Although they may use the same medication and have the same condition as you, you should never share medication with others.

 What if I miss a dose?

Apply the miss dose as soon as you remember. If you next dose is approaching soon, skip the miss dose and continue as normal.

How should I store this product?

Keep this medication in the original container it came in; ensure it is sealed tightly, away from heat and moisture and out of reach of children.

How fast till I feel relief after applying this lotion?

Skin conditions should improve within the first two weeks of treatment.

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