Depakote can cause liver failure, especially in children under the age of 2 and in people who suffer from liver problems as a result of a genetic disorder; this could be fatal.
If you have liver disease, a urea cycle disorder, low platelet counts, or a genetic disorder such as Alpers' disease or Alpers-Huttenlocher syndrome, your doctor will likely tell you that Depakote is not suitable for you. You may need to reconsider taking Depakote.
If you are pregnant, it is extremely important to follow your doctor’s directions; it is still very important to follow your doctor’s directions regardless; this medication could harm a baby but stopping the medication or taking it incorrectly could cause a fatal seizure for both the mother and unborn baby.
Do not use this as a migraine relief medication if you are pregnant; there are safer alternatives for migraines when you are pregnant.
If you have signs of liver or pancreas problems, contact your doctor right away (see side effects for signs to watch for).
If you have ever had depression, mental illness, suicidal thoughts or actions, or HIV or CMV infection, tell your doctor as you may need a dose adjustment or special cautions while taking Depakote.