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What is Dantrium?

Dantrium is an oral capsule made up of a skeletal muscle relaxant called dantrolene. We have Dantrium available for purchase in 25mg and 100mg.

Dantrium (dantrolene) is prescribed to patients who suffer from spasms (tightness and cramping) caused by nerve disorders which includes spinal cord injury, stroke, cerebral palsy, and multiple sclerosis. It can also be used to prevent or treat malignant hyperthermia (a special case of high fever) when used with other treatments. This is usually seen in cases related to anesthesia and surgery.

This muscle relaxer (Dantrium) helps to improve these conditions by inhibiting certain cells from releasing from certain antagonizing receptors and lessening the excitation and contraction coupling in muscles cells, reducing muscle pain and stiffness.

Always follow directions given to you by your doctor. Instructions can usually also be found on the prescription or prescription bottle/container.

Most patients start off on 25mg once a day for seven days and then a dose adjustment can be made. This tablet can be taken with or without food.

Take this medication at the same time every day to create a routine to avoid missing a dose. This medication should be used regularly to get the most benefit out of it.


Tell your doctor about all medications you are currently taking including prescription, over-the-counter, vitamins, and herbal remedies. Also be sure to mention any drug allergies you may have. If you’ve had allergic reactions to drugs in the past, write down what the signs were to show your doctor.

There are a few reasons why a person shouldn't take Dantrium. If a person is allergic to dantrolene or any other ingredient in Dantrium, they should not take this medication. Anyone who has liver disease or is taking Diltiazem or verapamil should make their doctor aware of their condition before proceeding to take Dantrium. You should also mention to your doctor if you are breastfeeding, pregnant or need spasticity to help keep your balance.

Liver problems can sometimes turn deadly and in rare cases, Dantrium has caused liver problems. Those more at risk are women older than 35 and taking other medications as well as Dantrium. Higher doses increase your chance for liver problem. Regular liver function tests should be taken to keep a close eye on side effects.

If your condition does not show signs of improvement after 45 days, talk to your doctor about alternate medications.

Those 65 or older may be more likely to experience side effects.

Side Effects

Common side effects of Dantrium may include:

  • Feeling sleepy.
  • Dizziness.
  • Feeling tired or weak.
  • Diarrhea.

The above side effects should not alarm you.

Serious side effects of Dantrium may include:

  • Choking.
  • Trouble swallowing.
  • Chest pain or pressure.
  • Shortness of breath.

If you have any of the above side effects, contact your doctor right away.        

Signs to watch for:

liver problems - dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

allergic reaction - rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. 


What if I miss a dose?

As soon as you remember; unless your next dose is approaching, then you may skip the missed dose and take your next dose as scheduled. Do not double up on doses.

What should I avoid while using Dantrium?

Avoid excessive and direct sunlight as this medication can make you sunburn more easily. Also avoid driving or doing other activities that require you to be alert until you know exactly how this medication affects you.

Is this safe to give to a child under 12?

You may need to monitor the child more carefully than you would an adult, however if the benefit outweighs the risk, Dantrium can be given to a child under 12.

What does Dantrium usually look like?

Dantrium is usually an oblong shaped capsule; orange and tan in color, though color and shape can sometimes vary.

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