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Danocrine is an oral tablet made up of an antigonadotropic agent called danazol. This medication has a generic alternative (same active ingredient; different in price, appearance and price) available for purchase as well as the name brand Danocrine in 50mg, 100mg, and 200mg.
Danocrine (Danazol) is prescribed to women to treat both pelvic pain and infertility that is the result of endometriosis (uterus disorder) and treats symptoms like breast pain, tenderness or nodules caused by fibrocystic breast disease (breast condition). However, it can also be used for both men and women when treating symptoms (swelling of abdomen, arms, legs, face, and airway) of hereditary angioedema (congenital disease).
Danazol works by decreasing the amount of certain hormones (that make the condition worse) made by the ovaries when treating uterus and breast conditions. When treating congenital diseases, danazol helps to create extra production of certain proteins (that help fight the condition) in your bodys defense system, also known as your immune system.
Only take this medication the way that your doctor has directed you too. Taking the incorrect dose can lead to unwanted side effects, ineffectiveness, or adverse interactions.
This medication is taken by mouth and is done usually twice a day. Your doctor should be able to clarify how often.
Take this medication the same way every time. If you take it with food the first time, always take it with food, and vice versa.
Use Danazol regularly to get the best results. If your condition does not improve or if it worsens, contact your doctor about alternative medications.
If you are a woman taking Danazol, you should start taking it around the start of your monthly menstrual cycle.
Some medical conditions as well as medications to treat those conditions shouldn’t be mixed with Danazol as they can cause unwanted adverse interactions and sometimes be fatal. Tell your doctor about all past medical conditions as well as all medications you are currently taking including prescription, over the counter, herbal supplements and vitamins, to determine if this medication is right for you. Below is a list of conditions in which you should not take Danazol:
Other conditions may be okay to take danazol with, as sometimes the benefits outweigh the risks and a simple dosage adjustment can be made. Below is a list of conditions you should mention to your doctor before taking danazol as you may need to take extra precautions:
You should not use this medication if you are pregnant. Taking danazol while pregnant could lead to birth defects or harm to the baby. Speak to your doctor about birth control methods before taking danazol, you may also need to take a pregnancy test before starting this medication.
Breast feeding is not recommended while using danazol as it passes into breast milk and could harm a nursing infant.
This medication should not be taken by anyone younger than 18 years old.
Side effects are not always present in everyone. Others are more sensitive to side effects while they could be mild for others. If side effects ever become too much to handle, contact your doctor right away.
Common side effects of danazol may include:
Serious side effects of danazol may include:
Speak to your doctor if you experience any of the side effects listed above.
Signs to watch for:
increased pressure inside the skull: severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or
blood clot: sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg.
What other drugs will interact with danazol?
Some medications that will react to danazol include;
insulin or oral diabetes medications; or
cholesterol lowering medicines such as atorvastatin, lovastatin, or simvastatin.
What if I miss a dose?
Skip the missed dose if your next dose is approaching. If it hasn’t been that long since you were suppose to take the missed dose, take it.
What else should I know?
Medical tests should be preformed regularly to monitor your progress. These tests include liver function tests and cholesterol level tests.
Is this safe for children to use?
No, the safety and effectiveness of danazol has not yet been established in children 0-18 years old.
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