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DDAVP (which stands for 1-deamino-8-D-arginine vasopressin) is an oral tablet made up of antidiuretic hormone called desmopressin. We carry the brand choice DDAVP in 0.1mg and 0.2mg.
DDAVP (Desmopressin) is a man made form of vasopressin (a natural hormone found in the pituitary gland) which has an effect on various body functions such as affecting blood pressure, kidney function, and regulating how the body uses water. When the body doesn’t have enough vasopressin, your kidneys may excrete an extra amount of water; this will cause a high frequency in needing to urinate, dehydration, and can even cause low blood pressure.
In conditions like diabetes insipidus (“water diabetes”) and in certain cases of head injury or brain surgery, the body does not produce enough vasopressin. DDAVP is prescribed to patients with those conditions to replace the loss vasopressin with desmopressin to control their possible excessive thirst and urination due to the condition. DDAVP works to treat these conditions by increasing the water permeability (how easily liquid and gas passes through something) in the renal tubular cells, decreasing the urine volume and increasing the urine concentration. This also helps decrease the chance of dehydration. DDAVP is also prescribed to those who cannot control their nighttime bedwetting.
DDAVP comes in other forms such as DDAVP Nasal Spray and DDAVP Melt (oral).
If you are taking DDAVP it is important to limit how much fluid intake you are getting. If you are drinking more fluids than suggested, speak with your doctor as you may need a dose adjustment.
Dosage is based on your response to treatment and medical condition.
Take this medication regularly to get the most benefit from it.
Take this medication by mouth, 2 or 3 times a day as directed by your doctor.
Take this medication by mouth once a day at bedtime. Limit fluid intake after dinner, mainly an hour before the dose, until morning time.
This medication may or may not harm an unborn child. Consult your doctor about the risk of DDAVP while pregnant if this concerns you.
It may not be safe to breastfeed while using DDAVP.
Do not give this medication to a child unless told to do so by your doctor.
Some medical conditions, as well as medications to treat those conditions, shouldn’t be mixed with DDAVP as they can cause unwanted adverse interactions and sometimes be fatal. Tell your doctor about all past medical conditions as well as all medications you are currently taking including prescription, over the counter, herbal supplements and vitamins, to determine if this medication is right for you. You may not be able to take DDAVP if you have the following:
You may need a dose adjustment if you use the following:
You may need to take DDAVP with extra caution if any of the following apply to you:
Common side effects of DDAVP may include:
The above side effects should not alarm you.
Serious side effects of DDAVP may include:
If you have any of the above side effects, contact your doctor right away.
Signs to watch for:
Low sodium: headache, confusion, hallucinations, muscle cramps, severe weakness, vomiting, loss of coordination, feeling restless or unsteady;
How fast does DDAVP work?
This medication should begin to work within 1 hour of taking the tablet.
What are the signs of overdose on DDAVP?
Overdose signs may include headache, confusion, drowsiness, rapid weight gain, or urination problems.
What are the four types of diabetes insipidus?
The four types of diabetes insipidus include central diabetes insipidus, nephrogenic diabetes insipidus, dipsogenic diabetes insipidus, and gestational diabetes insipidus.
Can I drink alcohol while on this medication?
Alcohol can interfere with the effectiveness of DDAVP. Consult your doctor to discuss a alcoholic beverage limit.
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