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Cytomel is an oral pill containing liothyronine, which is considered a thyroid drug. This pill is usually white in color but can vary depending on if you buy brand or generic. We have the generic version of Cytomel which is named after its active ingredient; liothyronine. This medication is available in 25mcg.

This medication is used mainly for adding thyroid hormones into your body when your body cannot produce it/enough of it, to manage thyroid cancer, and to test for thyroid problems. This is not a complete list of conditions it treats, but some of the more common ones. When a person has a low thyroid level, whether it’s natural or caused by an injury, their body process slows down. The thyroid is in charge of your bodys cells and how they use energy from food (metabolism). Metabolism affects your temperature, heartbeat and how well you burn calories.

Only take this medication the way that your doctor has directed you too. Taking the incorrect dose can lead to unwanted side effects, ineffectiveness, or adverse interactions.

Take this medication orally (by mouth) with or without food; do this once a day. Take this pill at the same time everyday to ensure a consistent hormone level is achieved.

For best effectiveness, take this medication around the same time every day. This will ensure you do not miss a pill as regular use is the best way to achieve results.

If you take colesevelam, colestipol, cholestyramine, kayexalate, or sevelamer, ensure it is not taken within the same 4 hours as Cytomel.


Tell your doctor about all medications you are currently taking including prescription, over-the-counter, vitamins, and herbal remedies. Also be sure to mention any drug allergies you may have.

Some medications may affect the absorption of liothyronine, some of these medications include: products that contain aluminum or magnesium, antacids, sucralfate, calcium supplements, iron, bile acid-binding resins (such as cholestyramine, colestipol, colesevelam), simethicone, sevelamer, sodium polystyrene sulfonate, among others.

Tell your doctor if you suffer from overactive thyroid gland or weak adrenal gland.

With high doses, there is a chance of weak bones (osteoporosis); this risk is higher in women who have experienced menopause.

If you have high blood sugar (diabetes), liothyronine (Cytomel) may raise your blood sugar.

Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding as you will need to talk about the benefits and risks to find out if you can take Cytomel.

Side Effects

Side effects are not always present in everyone. Others are more sensitive to side effects while they could be mild for others. If side effects ever become too much to handle, contact your doctor right away.

Common side effects of Cytomel (Liothyronine) may include:

  • Temporary hair loss (particularly in children)
  • Mild nausea

Serious side effects of Cytomel (Liothyronine) may include:

  • Chest pain or pounding in the chest
  • Rapid or irregular heartbeat
  • Rapid or irregular pulse
  • Leg cramps
  • Excessive sweating

Signs to watch for:

Too much thyroid hormone in the body: feeling bothered by heat; shaky; tired or weak; more or less hungry; nervous, excitable, or irritable; weight loss; fever; sweating a lot; headache; anxiety; emotional ups and downs; trouble sleeping; muscle weakness or cramps; fast or abnormal heartbeat; chest pain or pressure; shortness of breath, a big weight gain, or swelling in the arms or legs; diarrhea; throwing up; stomach cramps; flushing; bone pain; period (menstrual) changes; or fertility problems.

High blood pressure: very bad headache; dizziness; passing out; or change in eyesight.


How to take Cytomel?

This medication is taken orally, and can be taken with or without food. It is usually only taken once a day. Therefore, it is best to take it at the same time each day. Remember your dosage is based on your medical condition, age, lab test results and your overall response to the treatment.


How long does Cytomel stay in your system?

Cytomel can stay in our system for up to 48 hours.


How long does Cytomel take to start working?

You may begin to feel the effects of this medication within a few hours; however you may not begin to see the full effect for up to 2 to 3 days.


Where to buy Cytomel?

While you can purchase this medication at your local pharmacy, you may also find it on an online Canadian Pharmacy, such as My Drug Center. We have a starting price of $85.00 for 100 pills.


Who makes Cytomel?

Cytomel is manufactured by Pfizer Inc. The food and drug administration approved it for medical use in the year 1956.


Why is Cytomel so expensive?

Cytomel falls in line with Medicare’s Tier 2 formulary. Tier 2 means that the drug is a “non-preferred generic”.  This means that this medication will be expensive for the brand choice, while there may be some generics for some of these medications, which you can find on our website at My Drug Center. We have a starting price of $85.00 for 100 pills for Liothyronine, which is the generic for Cytomel.

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