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Cyclogyl is a solution made up of cyclopentolate, which is a anticholinergics. This medication usually comes in a white and red bottle, however sometimes it can be white and purple, white and green, or sometimes a combination of white and another color not listed. We carry the brand choice Cyclogyl in 1% dose bottles ranging from 15ml to 30mL bottles.

Cyclogyl Eye Drops (Cyclopentolate) are used before eye examinations (like a refraction test) but can also be used for the treatment of paralysis of the ciliary muscle of the eye, inflammation of the uvea of the eye and help prevent sticking of the iris to  the eye lens.

This eye solution relaxes the muscles in your eyes to dilate your pupils. When your pupils are dilated, they are wide which is needed to do most eye exams.

Cyclogyl Eye Drops are usually done by the ophthalmologist and are used about 40 – 50 minutes prior to the procedure. It may need to be repeated after about 10 minutes. Once the eye drops have been applied, avoid blinking and/or rubbing your eyes.

  • Wash your hands
  • Remove any eye contacts/lens
  • Tilt your head back and look up
  • Pull your lower eyelid down to form a pouch
  • Apply one drop into pouch
  • Look downward and close your eyes for 1-2 minutes
  • Place your finger at the corner of your eye closest to your nose and apply pressure for 2-3 minutes.


Always tell your doctor about your previous medical conditions as well as any drug allergies you may have. More importantly, tell your doctor if you have ever had personal or family history of glaucoma (angle-closure type), Down's syndrome, brain damage or spastic paralysis (in children), heart disease and if you have any allergies towards belladonna alkaloids (e.g., atropine).

After applying these eye drops, your vision will be temporarily blurred. Do not drive or use machinery until your vision comes back. This includes any activity where clear vision is required.

Cyclogyl Eye Drops may increase your sensitivity to light; bring a pair of sun glasses to your appointment for when it’s over.

Children have more of a chance to become effected by side effects of this medication, especially mental/mood changes. If a child is using this medication, make sure they are being closely monitored.

Elderly patients also may be more inclined to side effects, especially increased eye pressure.

Do not use this when pregnant unless you really need too, as directed by your doctor. It is not known if this medication passes through breast milk; it is recommended you do not breast feed while you are on this medication.

Side Effects

Common side effects include:

  • blurred vision;
  • mild eye irritation or redness;
  • puffy eyelids; or
  • the eyes being more sensitive to light.

Tell your healthcare provider if the following occur:

  • tunnel vision, eye pain, or seeing halos around lights;
  • severe burning or redness of your eyes;
  • drowsiness;
  • constipation, little or no urinating;
  • dry mouth or nose decreased sweating;
  • fast heartbeats; or
  • fever, skin rash, flushing (warmth, redness, or tingly feeling).

Since infants are more susceptible to side effects, monitor them for these side effects for at least 30 minutes after the child had the eye drops applied:

  • loss of coordination;
  • unusual changes in behavior;
  • feeling restless or excited;
  • confusion, speech problems; or
  • feeding problems, stomach bloating.


What is the best way to store these eye drops?

Store between 46-80°F OR 8-27°C. Keep away from heat and light, avoid freezing.

How long will the effects of the eye drops last?

They usually are gone within 24hrs however for some it may take a week before all effects are gone.

What are the signs of an allergic reactions?

Common symptoms of an allergic reaction include: sneezing and an itchy, runny or blocked nose (allergic rhinitis), itchy, red, or watering eyes (conjunctivitis), wheezing, chest tightness, shortness of breath, cough, a raised itchy, red rash (hives) or swollen lips, tongue, eyes or face.

How long do I have to wait before I can put my eye contacts back in?

It is suggested to wait up to 15 minutes before putting them back into your eyes after applying the medication.

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