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Cyclocort Cream is a high potency topical corticosteroid made up of amcinonide. You can buy this medication as the brand name Cyclocort Cream or just as its generic alternative/active ingredient, amcinonide. This cream is available in 0.10% bottles.

Cyclocort Cream is used for the relief of a variety of skin conditions often accompanied by inflammation. Some of these conditions include, but are not limited to, eczema, dermatitis, allergies and rash. Ideally this medication is used in patients between 18 and 65 years old. Amcinonide works by reducing the amount inflammation of the skin.

Ensure you use this cream exactly the way your doctor has told you to. It is always a good idea to wash your hands before starting to lessen the chance of bacterial infections. Continue using this cream even if you feel your condition has cleared up. Keep in mind that this medication is for topical use only; do not take this medication orally. Avoid putting this cream on your face, underarms or the groin unless specifically told to by your doctor.

Clean the area; ensure it is completely dry.

Add a thin layer of cream; gently rub in.

Do not cover; this also includes make up as well as clothing and bandages.


Make sure all of your health care providers (including dentists, nurses, and pharmacists) that you are using Cyclocort Cream. Before using this cream make sure you have told your doctor about all other skin medications you use.  Also make your doctor aware if you have ever had poor blood circulation or immune system problems.

Do not put Cyclocort Cream on any open wounds, cuts, scrapes or damaged skin.

It is rare however if Cyclocort Cream is used for a prolonged time and using it over large areas of the skin, sometimes difficulties arise for the body to respond to stress physically, therefore it is important to let whomever know before surgery what you are on.

During pregnancy, Cyclocort Cream should only be used if the doctor believes the benefits outweigh the risks.

It is not known if this medication passes into breast milk. Consult your doctor before breast feeding on Cyclocort Cream.

Side Effects

Please note this is not a complete list of side effects. Not everyone experiences side effects; they are not guaranteed. If you do have side effects and they become unmanageable, consult your doctor about alternate medications.

Common side effects of Cyclocort Cream may include:

  • Dry skin
  • Itching
  • Burning
  • Stinging

Serious side effects of Cyclocort Cream may include:

  • Change in color of skin
  • Skin changes (pimples, stretch marks, slow healing, hair growth)
  • Skin irritation
  • Thinning of the skin

Call your doctor right away if you have any serious side effects.

Signs to watch for:

  • Allergic reaction- rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • High blood sugar - confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • Cushing's disease - weight gain in the upper back or belly, moon face, very bad headache, or slow healing.
  • Weak adrenal gland - a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss.


What areas of the skin should I not apply Cyclocort Cream?

Areas to avoid applying Cyclocort Cream include the face, groin, underarms, or on acne, rosacea, puss-filled bumps, rashes, itchy skin, as well as avoiding areas with bacterial, fungal, parasitic viral skin infections, tuberculosis, skin lesions or skin reaction caused by a recent vaccination.

What other forms of Cyclocort are there?

Other forms include Cyclocort Ointment and Cyclocort Lotion.

What medications will interact with Cyclocort Cream?

There could be more; however, the two main interactions consist of Ritonavir (for HIV) and

Itraconazole (for fungal infections).

What temperature should I store Cyclocort Cream?

Store this medication between 15° and 25°C; do not freeze.

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