What is Comtan (Entacapone) prescribed for?

Comtan is a medication that is used with other medicines, such as levodopa, to treat Parkinson ’s disease. This is a disease that affects the nerve cells of the brain that produce dopamine. Symptoms include muscle rigidity tremors, and changes in speed and gait.

People taking levodopa are having the issue of the effects of levodopa wearing of between scheduled doses.  Comtan blocs a substance called COMT enzyme that breaks down the levodopa in the body. This effect allows the levodopa to last longer in the body’s system, so it doesn’t wear off before the next dose.

This medication comes in the singular dose, which is 200mg. Remember your dose is based on your medical background and your overall response to the treatment. If your doctor or pharmacist has given you some information in the form of a pamphlet, take the time to read up on this drug, and if you have any questions or concerns regarding this medication, please consult your doctor.

Take this medication by mouth, and can be taken with, or without food.  It is usually prescribed with levodopa, and up to 8 times daily, or as directed by your doctor.

This medication is based on your medical condition and your response to the treatment.  Use this medication regularly. DO not stop taking this medication unless explicitly instructed to by your doctor. Doing so may cause your Parkinson’s symptoms to become much worse.

Before taking this medication, inform your doctor if you are allergic to Entacapone, or if you have any other allergies in general.

Before using this medication it is always best to go over your medical history with your doctor, especially if you have had the following;  alcoholism, liver problems, low blood pressure, mental/mood disorders (such as depression, schizophrenia), sleep disorders.

Nausea, vomiting, diarrhea, unwanted/uncontrolled movements, increased sweating, drowsiness, tiredness, dry mouth, gas, and abdominal pain may occur. If any of these effects persist or worsen, tell your doctor promptly.

There is some serious side effects to this medication, and if you are encountering any of them, notify your doctor right away. These side effects are listed below; mental/mood changes (such as confusion, hallucinations), unusual strong urges (such as increased gambling, increased sexual urges), fever, muscle stiffness, persistent diarrhea, easy bleeding/bruising, sore/painful muscles, muscle weakness, trouble breathing, pain with breathing.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Some people taking entacapone have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some cases, sleep occurred without any feelings of drowsiness beforehand. This sleep effect may occur anytime during treatment with entacapone even if you have used this medication for a long time. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your risk of this sleep effect is increased by using alcohol or other medications that can make you drowsy. See also Precautions section.

What happens if I suddenly stop taking this medication?

There may be a relapse in symptoms as well as side effects. You should speak your doctor before stop taking this medication.

What is the best dosage to take?

The diagnosis with your doctor will be able to determine the best dosage for your treatment. Work with your doctor closely for dosage and dosing schedules.

What happens if I miss a dose?

You should take the missed dose as soon you realize you have forgotten. If the forgotten dose is closer to your next scheduled dose, take the next schedule dose to avoid overlapping in dose.

What is the best way to store this medication?

This medication is stored at room temperature, and should be kept away from children and pets. Do not throw away this medication in the wastebasket. If you are uncertain how to dispose of this medication speak with your pharmacist for help in safely disposing of this medication.