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Accuretic is an oral tablet that is usually light pink to white in color. This medication is generically known as Quinapril/Hydrochlorothiazide, and in general, a combination of ACE inhibitors (angiotensin converting enzymes) and diuretics (also known as water pills). It is used when trying to achieve lower blood pressure. Since high blood pressure (hypertension) can lead to heart attacks and strokes as well kidney problems, Accuretic is also used to help prevent those risks from occurring. There are other medical conditions and medications that will have an effect on the strength of your dosage prescribed by your doctor. These strengths include 10MG/12.5MG, 20MG/12.5MG, and 20MG/25MG. Accuretic should not be mistake as a cure for hypertension, as it is only used to help control and ease symptoms.

Quinapril and Hydrochlorothiazide, the main active ingredients in Accuretic, both have their own important part to play in treating high blood pressure. Quinapril, is the ACE inhibitor in the medication and Hydrochlorothiazide is the diuretic. Ace inhibitors lower blood pressure by first reducing pressure in the vessels and creating easier blood flow throughout the body. This is done by widening the blood vessels. Water pills (diuretics) retain potassium in your body and allow your kidneys to release sodium into your urine. When your urine contains a high level of sodium, more water from your blood is taken with it. This will reduce the amount of fluid in your arteries and veins thus reducing blood pressure.

Always follow directions given by your doctor. Accuretic should be stored in a place away from moisture and light in room temperature (20–25°C (68–77°F).

Do not chew this tablet; only swallow it whole with water (if needed). Food will not have an effect on the medication.

Cholestyramine or colestipol (and other bile acid-binding resins that lower cholesterol) should be taken at least 4-6 hours after taking Accuretic.

This medication may make you have to urinate and is suggested to be taken in the morning or 4 hours before bedtime.

Most patients take as follows:

Starting dosage: One 10MG/12.5MG tablet once a day

Increased dosage: One 20MG/12.5MG tablet once a day  

If necessary, next increased dosage: Two 10MG/12.5MG once a day

The common dosage is between One 10MG/12.5MG to 20MG/12.5MG once daily.

All dosages are taken once a day and should be taken around the same time daily to avoid missing a dosage.


Do not take this medication if you are pregnant or breastfeeding. If you take any of the medications or have any health issues listed below, speak to your doctor before taking Accuretic.

Blood pressure lowering medicine containing aliskiren or with medicines known as angiotensin receptor blockers (ARB) A neutral endopeptidase inhibitor, used to treat high blood pressure or heart failure All prescription medicine Over the counter medicine, supplements, vitamins or natural therapies Kidney problems or dialysis Liver or heart problems Symptoms of low blood pressure (light headedness and/or dizziness) Diabetes High levels of potassium or cholesterol Systemic Lupus Erythematosus (SLE), scleroderma or other autoimmune diseases Non-melanoma skin cancer

Be cautious and regularly check for skin lesions while taking Accuretic. Accuretic may increase the risk of non-melanoma skin cancer. This is seen in cases where one is taking high or extended dosages.

It is easier to become dehydrated while on Accuretic and is suggested to drink lots of water while exercising or if you are in the sun. This is crucial for those who excessively sweat.

It has not yet been established whether or not it is safe or effective for children to take Accuretic. Never give your medication to others even if they are experiencing the same condition as you.

Side Effects

Side Effects:

• feeling light-headed, dizzy or faint 

• dry cough

• headache

• feeling sick (nausea) or vomiting

• stomach pain

• diarrhea

• constipation

• unusual tiredness or weakness, fatigue

• sleepiness or drowsiness

• difficulty in getting or maintaining an erection (impotence)

• runny or blocked nose, or sneezing

• taste disturbances or loss of taste

• confusion or nervousness

• restlessness

• back pain

• indigestion

• sore throat and discomfort when swallowing

• rash.

These side effects are usually mild.


Speak to your doctor if you experience:

• eye pain, vision problems 

• blurred vision or yellow vision

• itchy or raised skin rash, hives or nettle rash

• muscle cramps

• symptoms of sunburn (such as redness, itching, swelling, blistering) which may occur more quickly than normal

• signs of anaemia such as tiredness, being short of breath and looking pale

• tingling or numbness in the hands, feet or ankles

• severe upper stomach pain, often with nausea and vomiting

• signs of worrying or frequent infections such as fever, severe chills, sore throat or mouth ulcers

• aching, tender or weak joints or muscles not caused by exercise

• passing little or no urine

• swelling of the hands, feet or ankles

• bleeding or bruising more easily than normal

• yellowing of the skin and/or eyes.

• new or suspicious skin lesions


What if I miss a dose? 

Do not double up on your next dosage. If your missed dosage isnt for a while yet, take your missed dosage late.

What if I overdose?

You can detect an overdose by watching for an increased heart beat, a change in urine passed, or if you feel light-headed, dizzy or the act of fainting. If this occurs, call 911 or poison control. You may need urgent medical attention.

Will Accuretic affect blood tests?

Yes, be sure to tell your doctor what medications you are taking before any blood tests. This applies before surgery as well.

Is it okay to drive under the influence of Accuretic?

Like many other medications, Accuretic may cause dizziness and operating vehicles should be done only when one knows how accuretic effects them.

Can I drink alcohol while taking this medication?

Alcohol can cause side effects to be more severe. Your doctor may advise you to cut down on alcohol intake.

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